Abstract: Objective  To search for the characteristic CT signs of the new coronavirus pneumonia(NCP) and to explore its clinical significance from the perspective of imaging pathology. Methods  CT images of 40 NCP patients in Hebei Province were collected and a total of 459 lesions in 234 lung segments on 72 sides were analyzed. Meanwhile,  CT images of totally 258 lesions in 79 lung segments on 28 sides of 20 non NCP patients randomly selected and treated in our hospital were compared with those of NCP patients above. Results  In NCP group,  the lesions were mostly located in the lower lobe of two lungs (30 cases,  accounting for 23.44%  respectively),  with bilateral involvement (32 cases,  accounting for  80.00%). The proportion of lesions involving 5 pulmonary lobes was relatively large,  with little difference in the distribution of left and right lung,  and only 1 case (2.50%)  with pleural effusion. There were significant differences between NCP group and nonNCP group in fanshaped shape,  peripheral distribution,  pulmonary hyperemia or pulmonary edema,  accompanied by vascular thickening and bronchial wall thickening. These suggested that the lesions of NCP were initially in the periphery and gradually infiltrate and fuses on the basis of fanshaped structures. And the lesions were mostly accompanied by vascular thickening and pulmonary hyperemia,  but with little bronchial wall thickening. Conclusion  The CT signs of NCP are characteristic，and they may be more likely to invade blood vessels and cause vasculitis,  which may lead to pulmonary edema and cardiopulmonary circulation disorder.

Key words: novel coronavirus pneumonia, fan structure, cardiopulmonary circulation disorder, computed tomography, pulmonary lobule