Abstract: Objective  To explore the evaluation value of red blood cell distribution width(RDW), neutrophiltolymphocyte ratio(NLR) and hypersensitive Creactive protein(hsCRP) levels on the severity of acute pancreatitis (AP).Methods  According to the Guidelines for the Diagnosis and Treatment of Acute Pancreatitis in China (Shenyang, 2019),  175 patients with AP were divided into mild and severe groups. General information and related indicators were compared between the two groups. The evaluation value of RDW, NLR, hsCRP and combined detection for AP severity were compared. Results  The RDW, NLR and hsCRP levels in the severe group were significantly higher than those in the mild group (P<0.05). RDW, NLR and hsCRP can all assess the severity of AP. The combined detection had a higher diagnostic efficiency for the assessment of AP severity, with the sensitivity and specificity of  90.9% and 90.8%, respectively, and the area under the curve (ACU) was significantly higher than that of RDW, NLR and hsCRP. ConclusionRDW, NLR and hsCRP can all assess the severity of AP to different degrees. Combined detection can improve the diagnostic efficiency of AP severity.

Key words:  pancreatitis, acute necrotizing, red blood cell distribution width, neutrophil to lymphocyte ratio, hypersensitive Creactive protein