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Study of intravoxel incoherent motion imaging in common renal cell carcinoma

  

  1. 1a. Department of Radiology; 1b. Second  Department of Radiotherapy and Chemotherapy， Handan Central Hospital， Handan 056001，China; 
    2. Department of Radiology， the Second Hospital of Hebei Medical University， Shijiazhuang  050000， China; 
    3.Second Department of Radiology， No.1 Hospital of Shijiazhuang， Shijiazhuang 050011， China
  • Online:2016-05-05 Published:2016-05-04
  • Contact: Corresponding author: Feng Pingyong，Email: xjfpy@163.com

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Abstract:

Objective  To use intravoxel incoherent motion(IVIM) diffusionweighted imaging of renal cell carcinoma (RCC) for comparing their imaging difference， so as to provide more valuable imaging basis for guiding clinical individualized treatment. Methods  A retrospective study was made in 49 patients with RCC  demonstrated by surgical pathology and imaged at 3.0T MRI using 8 b values for diffusionweighted imaging， the values of ADC and IVIM parameters were compared between different subtypes of RCC. Results  The values of ADC， pseudodiffusivity coefficient (D*) and perfusion fraction (f) of clear cell RCC(ccRCC)  or chromophobe RCC(chRCC) compared with papillary RCC(pRCC) had statistically significant difference (P＜0.05)， but the value of tissue diffusivity (D) demonstrated no significant difference. Conclusion  ccRCC and chRCC are hypervascular tumors， the values of ADC and IVIM parameters were no significant difference in the solid portion between ccRCC and chRCC. The values of ADC， D*and f were lower in pRCC than those of  ccRCC and chRCC. The value of D demonstrates no significant difference between common subtypes of RCC.

Key words: kidney neoplasms; , magnetic resonance imaging