Abstract: In recent years，with a rising trend in the incidence of inflammatory bowel disease(IBD) the pathogenesis of IBD is still clear. It may associate with heredity， immunity， infection and environmental factors. Helicobacter pylori (H.pylori) is a common gramnegative micro aerobic bacteria in the stomach， which is related to peptic ulcer and gastric malignancies. A correlation between IBD and H.pylori， is uncertain. This article reviews the relationship between IBD and H.pylori in order to have a thorough understanding of the etiology of IBD， and provides a new way of thinking for the clinical treatment of IBD and H.pylori.

Key words: inflammatory bowel diseases, helicobacter pylori, clinical protocols, immunity