Abstract: Objective   To investigate the correlation between the modified Crouse score， serum C reactive protein (CRP)  levels and neurological impairment (NIHSS score)  in acute cerebral infarction patients.Methods   153 participants who were diagnosed by CT or MRI as the first acute ACI elderly patients were enrolled from Jul. 2015 to Nov.  2016 in our hospital and the elderly physical examination patients were enrolled as the control group in  the same period . The carotid ultrasound and serum CRP were detected in two groups. Results   In ACI group， the plaque detection rate was 91.5%(140/153) and the total number of patch was 954. In control group， the detection rate of 70.0% (98/140) and the total number of patch was 378. The plaque detection rate of ACI group was significantly higher than that of control group（χ2=22.170，P＜0.05). The irregular echo plaques of ACI group were increased compared with those of control group (χ2=32.270，P<0.05). The plaque morphology in ACI group was composed with hybrid echo and hypoechoic plaques. However， the plaque morphology in  control group was mainly composed with homogeneous echo and hyperechoic plaque， ulcer plaque of ACI group also increased compared with that of control group (χ2=343.180，P<0.05). The serum CRP and the modified Crouse score in ACI group were significantly higher than those in control group (χ2=79.520，P<0.05). NIHSS ≤ 7 and NIHSS >7 group in CRP level and carotid artery plaque group serum Crouse score differences between groups were statistically significant (χ2=19.450，P<0.05). Conclusion   The number of irregular plaques， hypoechoic plaques and mixed echo patches increased in ACI patients. Moreover， the incidence of plaque， plaque score and serum CRP protein in ACI patients were higher. With the increase of NIHSS score， plaque score and CRP  in patients with ACI also increased.

Key words: brain infarction；carotid , arteries；ultrasonography, plaque, atherosclerotic, Creactive protein