Relation between platelet parameters and clinical classification and severity of acute coronary syndrome

doi:10.3969/j.issn.1004-583X.2017.06.009

Abstract

Abstract: Objective To investigate the association between platelet parameters and the clinical classification and the severity of coronary artery disease in patients with acute coronary syndrome(ACS). Methods A total of 262 patients with ACS were divided into STEMI group (n=167)， NSTEMI group (n=30) and UAP group (n=65). The severity of coronary stenosis was quantitated by Gensini score system. The clinical data of three groups were compared， the correlation between Gensini score and clinical indexes were analyzed. Results There were significantly higher levels of age， hsCRP， mean platelet volume and platelet distribution width in STEMI group and NSTEMI group than in UAP group（P<0.05）， MPV and PDW in STEMI group were significantly higher than those of NSTEMI group（P<0.05）. Correlation and regression analysis showed there were significant positive correlations between MPV， PDW and hsCRP levels and coronary lesions and Gensini score in all patients with ACS. Conclusion MPV and PDW levels were significantly different in patients with different ACS types， and the levels of MPV and PDW were positively correlated with the severity of coronary artery lesions in patients with ACS， which could be used as predictors of the severity of coronary artery lesions in patients with ACS.

Key words: acute coronary syndromes, blood , platelets, gensini score

Teng Xin1， Qin Qin2， Lu Yaru2， Yang Ning2. Relation between platelet parameters and clinical classification and severity of acute coronary syndrome[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2017.06.009.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2017.06.009

https://huicui.hebmu.edu.cn/EN/Y2017/V32/I6/487

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Relation between platelet parameters and clinical classification and severity of acute coronary syndrome

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