中药汤剂与穴位注射联合三氧治疗带状疱疹后遗神经痛的临床疗效

doi:10.3969/j.issn.1004-583X.2017.06.012

临床荟萃

中药汤剂与穴位注射联合三氧治疗带状疱疹后遗神经痛的临床疗效

1.酒泉市人民医院 a.神经外科；b.中医科；c.皮肤科；d.检验科，甘肃酒泉 735000；2.酒泉市疾控中心地方病科，甘肃酒泉 735000

出版日期:2017-06-05 发布日期:2017-06-01
通讯作者: 通信作者：王东雁，Email:Wangdongyan196548@126.com
基金资助:
甘肃省中医药管理局基金项目课题（GZK-2016-37）

Clinical efficacy of Chinese medicine decoction combined with point injection of three oxygen therapy in patients with postherpetic neuralgia

1a.Department of Neurology; b.Department of Traditional Chinese Medicine; c.Department of Dermatology;
d.Department of Laboratory， People's Hospital of Jiuquan，Jiuquan 735000， China;
2.Department of Endemic Disease，Center for Disease Control of Jiuquan，Jiuquan 735000， China

Online:2017-06-05 Published:2017-06-01
Contact: Corresponding author: Wang Dongyan，Email:Wangdongyan196548@126.com

摘要/Abstract

摘要： 目的观察中药汤剂与穴位注射联合三氧治疗对带状疱疹后遗神经痛（PHN）患者的临床疗效。方法选择PHN患者105例为研究对象，按随机数字表法分为3组，A组给予中药汤剂自拟方通络止痛汤；B组给予阿霉素穴位注射；C组给予中药汤剂与穴位注射联合三氧治疗。共治疗2周，观察治疗前后视觉模拟评分（VAS），检测静脉血清白细胞介素（IL）2、IL6、IL8和前列腺素E2（PGE2）水平，记录神经痛持续时间比较临床疗效。结果治疗前3组VAS评分、IL2、IL6、IL8、PGE2水平等比较差异无统计学意义（P>0.05）；治疗后3组各项指标较治疗前下降，且C组的降低程度较A、B组更明显（P<0.05）；与A、B组比较，C组总有效疗率明显提高（P<0.05）。结论中药汤剂与穴位注射三氧三级治疗方案具有活血舒筋之功效，可抑制炎症因子减轻痛觉，提高患者免疫状态改善局部血液循环，提高临床效果。

关键词: 神经痛, 带状疱疹后；止痛剂(中药), 白细胞介素2, 地诺前列酮

Abstract: Objective To observe the clinical effect of Chinese medicine decoction combined with acupoint injection ozone (three oxygen) on the patients with postherpetic neuralgia (PHN). Methods A total of 105 cases of PHN patients were selected as the study subjects， and divided into three groups according to the random number table method， group A was given traditional Chinese medicine; group B adriamycin by acupoint injection; group C traditional Chinese medicine decoction combined with acupoint injection of three oxygen treatment. Giving a total of two weeks of treatment， the visual analogue scale (VAS) was observed before and after treatment， the levels of IL2， IL6， IL8 and PGE2 in venous serum were detected and the duration of neuralgia was recorded to evaluate the clinical efficacy.Results There were no significant difference in the VAS scores， the levels of IL2， IL6， IL8， PGE2 among three groups (P>0.05); After treatment， the indicators in three groups were significantly lower than those before treatment (P<0.05); The indexes of group C showed more decrease than those of group A and B， the duration of neuralgia and the total effective rate in group C were significantly higher than those of group B. The levels of IL2， IL6， IL8， PGE2 and VAS in group A were significantly decreased (P<0.05); Compared with group A and B， the duration of neuralgia in group C was significantly decreased and the total effective rate was significantly improved (P<0.05). Conclusion The threelevel treatment of Chinese medicine decoction combined with acupoint injection of three oxygen showed the effect of promoting blood circulation， inhibited inflammatory factors to reduce pain， and improved immune status of patients， local blood circulation and clinical outcomes.

Key words: neuralgia, postherpetic, analgesic agents (tcd), interleukin2 dinoprostone

景兆德1a，王东雁1b，宋卫东1a，陈敬德1c，柴峰1a，王勇1a，丁俊2，马彪泰1d. 中药汤剂与穴位注射联合三氧治疗带状疱疹后遗神经痛的临床疗效[J]. 临床荟萃, doi: 10.3969/j.issn.1004-583X.2017.06.012.

Jing Zhaode1a， Wang Dongyan1b， Song Weidong1a， Chen Jingde1c， . Clinical efficacy of Chinese medicine decoction combined with point injection of three oxygen therapy in patients with postherpetic neuralgia[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2017.06.012.

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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2017.06.012

https://huicui.hebmu.edu.cn/CN/Y2017/V32/I6/498

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中药汤剂与穴位注射联合三氧治疗带状疱疹后遗神经痛的临床疗效

Clinical efficacy of Chinese medicine decoction combined with point injection of three oxygen therapy in patients with postherpetic neuralgia

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