关键词: 脑膜炎, 惊厥, 危险因素

Abstract: Objective  To explore the risk factors of purulent meningitis complicated with convulsion. Methods  The data of 86 children with purulent meningitis admitted in our department were retrospectively analyzed. The patients were divided into observation group and control group according to the presence of convulsion. Clinical features， cerebrospinal fluid (CSF)  laboratory examination and etiology examination were collected， and the multivariable logistic regression analysis was used to evaluate statistical differences. Results  Serum sodium （<135 mmol/L）  and cerebrospinal fluid leukocyte count （<1 000×106/L）  were significantly higher in observation group than in control group (P<0.05); there were no significant difference in the contents of protein or sugar of cerebrospinal fluid between two groups; there were significant differences in Streptococcus pneumoniae positive rate between two groups  (P<0.05)， and there were no significant difference in the positive rate of Haemophilus influenza and other species between two groups. Multivriable logistic regression analysis was performed in children with purulent meningitis suffering from convulsions and showed that children under two years old， consciousness disorder，Streptococcus pneumoniae and serum sodium  (<135 mmol/L)  were the risk factors for children with purulent meningitis complicated with convulsion. Conclusion  Children with purulent meningitis complicated with convulsion are related with age under two years old， disorder of consciousness， Streptococcus pneumoniae  and blood sodium less than 135  mmol/L.

Key words: meningitis, convulsion, risk factors