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磁敏感加权成像突出血管征在卒中患者中的应用价值

  

  1. 河北医科大学第三医院 神经内科,河北 石家庄 050000
  • 出版日期:2017-09-05 发布日期:2017-09-08
  • 通讯作者: 通信作者:刘俊艳,Email: junyanliu2003@163.com
  • 作者简介:刘俊艳,硕士生导师、二级教授。河北医科大学第三医院神经内科主任,河北省青年突出贡献专家,白求恩专家委员会常委,国家卫计委脑卒中防治委员会委员。中国卒中学会 委员,中国卒中学会脑血流和代谢分会副主委,中国医师学会委员,中国医师学会脑血管学组委员,河北省卒中学会副主委,河北省质量控制专家委员会副主委,河北省医学会神经病学分会 副主任委员。

Application value of prominent vessel sign on magnetic susceptibility weighted imaging in stroke

  1. Department of Neurology, the Third Hospital of Hebei Medical University, Shijiazhuang 050000, China
  • Online:2017-09-05 Published:2017-09-08
  • Contact: Corresponding author: Liu Junyan,Email:junyanliu2003@ 163.com

摘要: 急性卒中患者低灌注区域内脑组织局部血管内氧摄取率增高,导致毛细血管及静脉内脱氧血红蛋白与含氧血红蛋白比值增高。利用磁敏感加权成像对脱氧血红蛋白等顺磁性物质的敏感性,脱氧血红蛋白浓度高的血管在SWI上呈现为突出血管征(prominent vessel sign,PVS)。PVS的出现可用于评估缺血半暗带及脑灌注疗效,也预示了侧支循环建立及脑储备能力,PVS的存在也与卒中预后有一定关系。

关键词: 卒中, 磁敏感加权成像, 突出血管征

Abstract: In the patients with acute stroke, the oxygen extraction fraction(OEF) is increased in the hypoperfused parenchyma, resulting in an increase in the ratio of deoxygenated hemoglobin to oxygenated hemoglobin in the capillary and vein.  Because Susceptibility weighted imaging(SWI) is exquisitely sensitive to paramagnetic substances,   such as deoxyhemoglobin,prominent vessel sign(PVS) will appear on SWI when the concentration of deoxyhemoglobin in the veins increases. The presence of  PVS can be used to assess ischemic penumbra and cerebral reperfusion therapy, and also predict the establishment of collateral circulation and brain reserve capacity. Moreover, the presence of  PVS is also related to the prognosis of stroke.

Key words: stroke, susceptibility weighted imaging, prominent vessel sign