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摘要: 儿童生长激素缺乏症是导致儿童矮小的原因之一,生长激素激发试验是诊断儿童生长激素缺乏症的重要依据,但也存在假阳性,需要结合生长指标综合评价。生长激素缺乏症分为单纯生长激素缺乏症和多种垂体激素缺乏症,单纯生长激素缺乏症生长激素治疗效果好,需要进行动态的治疗监测,多种垂体激素缺乏症需要激素替代治疗,两者的生长激素缺乏均可能持续至成年期,且单纯生长激素缺乏症可能发展为多种垂体激素缺乏症,需要动态的监测及终身随访。
关键词: 生长激素, 生长激素激发试验, 治疗监测
Abstract: Growth hormone deficiency in children is one of the causes of short stature. Growth hormone stimulation test is an important basis for the diagnosis of growth hormone deficiency in children, but there are also false positives.And the test, together with target indexes,is comprehensively evaluated. Growth hormone deficiency can be divided into isolated growth hormone deficiency and multiple pituitary hormone deficiency. The growth hormone therapy is effective for isolated growth hormone deficiency, but dynamic monitoring is needed. Multiple pituitary hormone deficiency needs hormone replacement therapy. The growth hormone deficiency of both types may last into adulthood, and isolated growth hormone deficiency may develop into multiple pituitary hormone deficiency, and dynamic monitoring and followup for life is needed.
Key words: growth hormone, growth hormone stimulation test, treatment monitoring
李玉倩,皮亚雷,张亚男,崇禾萌,张会丰. 儿童生长激素缺乏症[J]. 临床荟萃, doi: 10.3969/j.issn.1004-583X.2019.10.003.
Li Yuqian, Pi Yalei, Zhang Yanan, Chong Hemeng, Zhang Huifeng. Growth hormone deficiency in children[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2019.10.003.
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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2019.10.003
https://huicui.hebmu.edu.cn/CN/Y2019/V34/I10/880