关键词: 肥胖症, 血脂异常, 高尿酸血症

Abstract: Objective  To investigate the incidence of hypertension,   nonalcoholic fatty liver disease,  abnormal glucose metabolism,  and blood lipid disorders in obese children by analyzing the blood lipids,   fasting blood glucose,   fasting insulin,   liver function,   and liver color Doppler ultrasound,  to help early identification and intervention of childhood obesity.Methods  Physical examination was performed on 103 obese children,   thenthe testing results of their blood lipids,  liver function,   fasting blood glucose,   fasting insulin,   2 h postprandial blood glucose,   and liver ultrasound were analyzed.Results  The survey found that there were statistically significant differences in triglyceride,   total cholesterol,   high density lipoprotein (HDL),   low density lipoprotein,   diastolic and systolic blood pressure,   and insulin resistance index among three groups of obese children (P<0.05). With the increase of body weight,   nonHDLC,   blood pressure,   and insulin resistance index showed an upward trend,  while HDLC decreased. Of 103 obese children,  19 (18.4%)  had hypertension; 36(35.0%) had dyslipidemia; 18 (175.5%)  had abnormal glucose metabolism,  of which,   2 cases(1.9%) had type 2 diabetes,  and children with the type 2 diabetes were moderately to severely. There were 24 patients (23.3%) with nonalcoholic fatty liver,   including 14 (13.6%)  with abnormal liver function.Conclusion  Childhood obesity can cause blood glucose,  abnormal blood lipids,  insulin resistance,  which increases the risk of hypertension, nonalcoholic fatty liver and diabetes in children. The obese childern must lose their weight  and do regular physical examinations to adjust the levels of various indicators and reduce the incidence of various complications caused by obesity.

Key words: obesity, dyslipidemias, hyperuricemia