临床荟萃
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摘要: 慢性肾脏病(CKD)已经成为危害公共安全的健康问题,患病率高,合并症多,预后差,而矿物质和骨异常(MBD)是其常见并发症,严重影响CKD患者的生活质量和生命安全,早期诊治是改善预后的关键。CKDMBD是一复杂的临床病理生理过程,有多种因素参与,本文将就CKD时MBD的发生机制、临床评估和诊治进展进行综述,以期为提高临床诊治水平提供有益的指导。
关键词: 肾功能不全, , 慢性;矿物质和骨异常;甲状旁腺功能亢进症, , 继发性; 钙磷代谢紊乱; 高磷血症
Abstract: Chronic kidney disease(CKD)has become a public health problem with high prevalence, multiple complications and poor prognosis. Being one of its common complications, while mineral and bone abnormalities can lower the quality of life and safety of patients with CKD. Early diagnosis is crucial for improving the prognosis of patients. Given CKDMBD is a complex clinical pathophysiological process with multiple factors involved, the pathogenesis, clinical evaluation, diagnosis and treatment of mineral and bone metabolic abnormalities caused by CKD will be reviewed. so that useful guidance for improving clinical diagnosis and treatment can be provided.
Key words: renal insufficiency, , chronic;mineral and bone disorde; hyperparathyroidism, , secondary ;disturbance of calciumphosphorus metabolism;hyperphosphatemia
陈云爽,杨新军,林静,王丽晖,吴广礼. 慢性肾脏病矿物质和骨异常的临床特征[J]. 临床荟萃, doi: 10.3969/j.issn.1004-583X.2018.10.002.
Chen Yunshuang, Yang Xinjun, Lin Jing, Wang Lihui, Wu Guangli. Clinical features in chronic kidney diseasemineral and bone disorder[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2018.10.002.
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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2018.10.002
https://huicui.hebmu.edu.cn/CN/Y2018/V33/I10/834