关键词: 大气, 颗粒物, 心血管疾病, 健康调查, 脂蛋白类,  , LDL, 磷脂酶A

Abstract: Objective  To investigate the effects of atmospheric particulates in indoor and outdoor working environment on inflammatory markers of the cardiovascular system in healthy people. Methods  A questionnaire survey was conducted amongthe residents aged 3060 in Shijiazhuang urban area according to their work situation (indoor group and outdoor group)from October to December 2018. Physical examination (including blood pressure,height, weight and etc), carotid ultrasound, and blood tests (including oxidized low density lipoprotein ［OxLDL］, serum lipoproteinassociated phospholipase A2 ［LpLPA2］, blood lipids and etc)  were carried out on the residents who met the eligibility criteria, then the statistical results were analyzed. Results  The educational level and risk factors related to cardiovascular system diseases including abdominal circumference, hip circumference,  systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol,  and highdensity lipoprotein cholesterol in the outdoor group were significantly different from those in the indoor group（P＜0.05). Conclusion  Atmospheric particulate matter in outdoor working environment may have no significant effects on markers associated with cardiovascular diseases including OxLDL and LpLPA2. However, it can increase blood pressure, fasting blood glucose, abdominal circumference, hip circumference, BMI and decrease HDLC, which may increase the incidence of cardiovascular diseases.

Key words: atmosphere, particulate matter, cardiovascular diseases, healthy surveys, lipoproteins, , LDL, phospholipases A