临床荟萃

• 论著 • 上一篇    下一篇

超声评价2型糖尿病患者并发原发性肝癌特点及相关因素分析

  

  1. 1.兰州大学第二医院  超声科,甘肃 兰州 730000;2.兰州石化总医院 超声科,甘肃 兰州 730060
  • 出版日期:2017-10-05 发布日期:2017-10-10
  • 通讯作者: 通信作者:聂芳,Email:fangnie@163.com

Characteristics of type 2 diabetes mellitus patients with primary liver cancer by ultrasonographic and risk factor analysis

  1. 1.Department of  Ultrasound, the Second Hospital of Lanzhou University, Lanzhou 730000,  China; 
    2.Department of  Ultrasound, General Hospital of Lanzhou Petrochemical Company, Lanzhou 730060,  China
  • Online:2017-10-05 Published:2017-10-10
  • Contact: Correspondingauthor:Nie Fang,Email:fangnie@163.com

摘要: 目的 观察2型糖尿病(T2DM)患者并发原发性肝癌的超声特点,并分析其原发性肝癌发生的相关危险因素。方法 分析85例T2DM合并原发性肝癌患者的临床资料及超声检查结果。取同期接受检查的不伴恶性肿瘤的T2DM患者87例作为对照组,与病例组进行比较分析,对相关危险因素进行多因素分析。结果 85例T2DM合并原发性肝癌患者肝脏病灶的超声特点:以肝右叶单发为主;形态较规则、边界清晰;病灶内部回声以低回声为主;病灶大小多在3~5 cm之间。彩色多普勒检测结果:病灶内部及周围血流均以Ⅲ级为主,呈高速高阻血流频谱。多因素Logisitic回归分析显示:男性、年龄、饮酒、高糖化血红蛋白(HbA1c)和乙型肝炎表面抗原(HBsAg)阳性是T2DM患者并发原发性肝癌的独立危险因素。结论 二维及彩色多普勒超声对肝癌的诊断具有重要意义。男性、年龄、饮酒、高HbA1c和HBsAg阳性是T2DM患者并发原发性肝癌的独立危险因素。

关键词: 糖尿病, 2型;肝肿瘤;超声检查;危险因素

Abstract: Objective  To observe the characteristics of type 2 diabetes mellitus patients with primary liver cancer by ultrasonic method and analyze risk factors. Methods  Eightyfive cases of type 2 diabetes mellitus patients with primary liver cancer were observed with color Doppler characteristics. A total of 87 patients with type 2 diabetes mellitus patients without any cancer who did the same examination at the same period were assigned as the control group. The risk factors were analyzed by multivariate analysis. Results  Ultrasonographic features of liver lesions in 85 patients with T2DM complicated with primary liver cancer: the right of the liver was mainly monotonous. Most of the lumps grew regularly and had clear boundary. The echo image inside of lumps was mostly hypoechoic and the size of lumps ranged between 3 to 5 cm. The liver right lobe was the main one, the shape was regular and the boundary was clear. The echo of the lesion was mainly hypoechoic, and the size of the lesion was between 35  cm. Doppler ultrasonic results: lesions within and around the blood flow were mostly Ⅲ class, showing highspeed and highresistance blood flow spectrum. The logisitic regression analysis showed that gender, age, drinking, HbA1C and HbsAg (+) were independent risk factors. Conclusion  The two dimensional and Doppler ultrasonic characteristics are valuable for diagnosis of the type 2 diabetes mellitus patients with liver cancer.  Male, age, drinking, HbA1c and chronic hepatitis B are independent risking factors in type 2 diabetes mellitus patients with prtmary  liver cancer.

Key words: diabetes mellitus, type 2, liver neoplasms, ultrasonography characteristics, risk factors