关键词: A2DS2评分, 急性缺血性脑卒中, 卒中相关性肺炎

Abstract: Objective  To explore the incedence of strokeassociated pneumonia (SAP) and assess the value of A2DS2 score in predicting SAP in patients with ischemic stroke in emergency ward. Methods  Baseline characteristics and laboratory data of 271 patients with ischemic stroke in emergency ward from April 1,   2014 to March 31,   2017 were analysed. Patients were allocated into SAP group (n=103) and nonSAP group (n=168). The multivariable logistic regression was applied to investigate risk factors for the progression of SAP. Receiver operating characteristic curve (ROC) was used to evaluate the predictive effect of A2DS2 score for ischemic strokeassociated pneumonia. Results  Totally,  103 (38.0%) patients developed SAP. There were significant differences between the two groups in terms of age, dysphagia,   National Institute of Health stroke scale scores (NIHSS),   comorbidities (atrial fibrillation,  ecoronary heart disease and history of stroke) and conscious disturbance (Glasgow coma score <9)  all of which were of statistical difference. The multivariable logistic regression analysis revealed that age over 75 years old,   dysphagia,   higher NIHSS and conscious disturbance were the risk factors for the development of SAP. The area under the ROC curve (AUC) of A2DS2 score for predicting strokeassociated pneumonia was 0.928. Conclusion A2DS2 score provides an effective method for prediction of the risk of ischemic strokeassociated pneumonia.

Key words: A2DS2 score, acute ischemic stroke, Strokeassociated pneumonia