关键词: 心血管疾病, 预后, 脉搏波传导速度, 踝肱指数

Abstract: Objective  To investigate whether pulse wave velocity and anklebrachial index  are related to the prognosis of patients with cardiovascular disease,  and whether the traditional monitoring indexes are still meaningful after the introduction of the new prognostic index. Methods  A total of 353 patients were included. The clinical data of patients were analyzed retrospectively and they were followed up after hospital discharge. Multivariate logistic regression analysis and propensity score matching  were used to determine whether the vascular function indicators were independent influencing factors for poor prognosis of patients with cardiovascular disease. Results  During the followup, totally 53 patients had cardiovascular events, and 11 cases died. Compared with patients in nonevent group,  patients in event group had higher risk of  heart failure and were more likely to have angiotensinconverting enzyme inhibitors/angiotensin receptor antagonists(ACEI/ARB),  and the anklebrachial index was smaller. Compared with patients in the survival group, the anklebrachial index was smaller in the allcause death group. Heart failure and ACEI/ARB were independent risk factors for the prognosis of patients with cardiovascular disease,  and anklebrachial index was an independent factor for death. Heart failure and anklebrachial index were independent risk factors influencing prognosis of patients with cardiovascular disease after propensity score matching. In the coronary heart disease subgroup analysis, gender,  heart failure,  stroke,  and ACEI/ARB drugs were independent risk factors for prognosis, while the anklebrachial index  was an independent factor for the death of  patients with cardiovascular disease.Conclusion  The anklebrachial index  was an independent factor for the prognosis of patients with cardiovascular diseases. After the introducing of vascular function monitoring indicators,  only anklebrachial index  and heart failure had predictive value for the prognosis of cardiovascular patients, while traditional cardiovascular risk factors had no predictive value.

Key words: cardiovascular diseases;prognosis, pulse wave velocity, anklebrachial index