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原发性高血压患者红细胞分布宽度与血压水平、中心动脉压及血压变异性的相关性

  

  1. 河南省人民医院 高血压科,  河南 郑州  450003
  • 出版日期:2020-08-20 发布日期:2020-06-24
  • 通讯作者: 刘敏,Email: southhlm@126.com
  • 基金资助:
    河南省医学科技攻关计划普通项目----维生素D与原发性高血压血浆肾素浓度及血尿酸关系研究(201702200)

Correlation  of red cell distribution width with blood pressure levels,  central arterial pressure

  1. Department of Hypertension,  Henan Provincial People's Hospital,  Zhengzhou 450003,  China
  • Online:2020-08-20 Published:2020-06-24
  • Contact: Corresponding author:Liu Min,Email: southhlm@126.com

摘要: 目的  探讨原发性高血压患者红细胞分布宽度(RDW)与血压水平、中心动脉压及血压变异性的相关性。方法  选择河南省人民医院确诊的原发性高血压患者531例。以RDW四分位数为截点,将患者分为4组[A1组(n=138), A2组(n=137), A3组(n=132), A4组(n=124)]。比较4组血压水平、中心动脉压及血压变异性的相关性。结果  4组间24小时平均收缩压(SBP),白昼平均SBP,4组间夜间SBP,4组中心动脉压差异有统计学意义(P<0.01)。各组间全天SBP变异系数、白昼SBP变异系数和夜间SBP变异系数差异有统计学意义(P<0.01),A4组显著高于其他3组。相关分析结果显示,RDW与24小时平均SBP、白昼平均SBP、夜间平均SBP、全天SBP变异系数、白昼SBP变异系数、夜间SBP变异系数和中心动脉压呈正相关关系。结论  原发性高血压患者RDW与血压及血压变异性中心动脉压呈正相关。

关键词: 原发性高血压, 红细胞分布宽度, 血压水平, 中心动脉压 , 血压变异性

Abstract: Objective   To investigate the correlation of red cell distribution width (RDW) with blood pressure levels,  central arterial pressure and blood pressure variability in patients with essential hypertension (EH). Methods   A total of 531 EH patients in Henan Provincial People's Hospital were selected. With RDW quartile as the cutoff point, the patients were divided into four groups (group A1 n=138,  group A2 n=137,  group A3 n=132,  and group A4 n=124). The blood pressure levels,  central arterial pressure and blood pressure variability were compared among four groups. Results  24hour mean systolic blood pressure (SBP), daytime SBP, night SBP, and central arterial pressure of four groups showed significant difference among four groups(P<0.01). The allday coefficient of variation (CV),  daytime CV,  nighttime CV had significant difference among four groups (P<0.01),  and  group A4  was significantly higher than that of  other groups.  RDW was positively correlated with 24hour SBP,  daytime SBP,  nighttime SBP,  allday CV,  daytime CV,  nighttime CV and central arterial pressure.Conclusion  RDW was positively correlated with blood pressure,  blood pressure variability   and central artery pressure in patients with EH.

Key words: essential hypertension;red cell distribution width;blood , pressure level;central arterial pressure;blood pressure variability