关键词: 呼吸功能试验, 流行病学研究, 小气道功能障碍

Abstract:

Objective To investigate the baseline characteristics, epidemiological characteristics and pulmonary function-related parameters of people aged ≥40 years in rural areas of Laiyuan County, Baoding. Methods Multi-stage stratified cluster random sampling method was applied to select rural residents aged ≥40 years old in public health center, and the combination of centralized survey and household survey was adopted to close the completion of questionnaires and lung function tests. Results A total of 700 respondents were selected for surveying, 655 cases with the pass rate of 93.6% were effectively surveyed. Wherein, 394 respondents were males, 261 respondents were females, and the age was ranged between (49.49±6.17) years old. The population with the total smoking rate of 43.4% (n=284) and smoking index ≥15 (cigarettes/day×years) accounted for 43.4% of the total population (n=284). The pulmonary function showed forced vital capacity (FVC) of (3.60±0.86) L, forced expiratory volume in the 1st second (FEV1) of (2.80±0.63) L, FEV1/FVC of (78.09±6.23)%, maximal mid-expiratory flow (MMEF) 75/25%pre of (60.69±22.59)%, forced expiratory flow (FEF) 50% pre of (74.98±23.70)%, FEF75% pre of (56.27±22.53)%. 123 cases (18.8%) were found to have small airway dysfunction, 56 cases (8.5%) were noted to have restrictive ventilation dysfunction, and 211 cases (32.2%) were confirmed to have obstructive ventilation dysfunction. Conclusion The morbidity rate of small airway dysfunction, restrictive ventilation and obstructive ventilation in people aged ≥40 years in rural areas (Laiyuan County) was 18.8%, 8.5% and 32.2%, respectively. The research on obstructive airway disease becomes necessary in the future to analyze corresponding independent factors, and further to prevent and treat related factors.

Key words: respiratory function tests, epidemiologic studies, small airway dysfunction