临床荟萃 ›› 2023, Vol. 38 ›› Issue (4): 352-355.doi: 10.3969/j.issn.1004-583X.2023.04.011

• 论著 • 上一篇    下一篇

获得性免疫缺陷综合征合并重症肺炎1例并文献复习

周大伟a, 费长东a, 刘宇鹏b, 张华霖a()   

  1. 解放军联勤保障部队第967医院 a.急诊医学科;b.重症医学科,辽宁 大连116000
  • 收稿日期:2022-09-14 出版日期:2023-04-20 发布日期:2023-06-06
  • 通讯作者: 张华霖 E-mail:dragon1218@126.com

Acquired immune deficiency syndrome complicated with severe pneumonia: A case report and literature review

Zhou Daweia, Fei Changdonga, Liu Yupengb, Zhang Hualina()   

  1. a. Department of Emergency Medicine; b. Department of Critical Care Medicine, 967 Hospital of the Joint Logistics Support Force of PLA, Dalian 116000, China
  • Received:2022-09-14 Online:2023-04-20 Published:2023-06-06
  • Contact: Zhang Hualin E-mail:dragon1218@126.com

摘要:

目的 探讨艾滋病患者因机会性感染引起的严重肺炎经验性联合用药及综合治疗的效果。方法 回顾性分析解放军联勤保障部队第967医院收治的1例以严重肺炎为主要表现的艾滋病病例的诊治过程,并复习文献加以讨论。结果 患者为中年男性,艾滋病病史近2年。因“体重减轻半年,发热咳嗽1个月,加重伴呼吸困难3d”入院,住院后明确诊断:①重症肺炎;②Ⅰ型呼吸衰竭;③艾滋病。经气管插管、呼吸机辅助呼吸、联合抗生素、肠内营养治疗后出院。2个月后来院复诊无发热、咳嗽、咳痰症状,复查胸部CT:右肺中叶局限性肺气肿,双肺炎症已吸收,肝功、肾功正常。结论 在无病原学依据的情况下结合病史、检验检查及既往治疗情况给予经验性联合用药对艾滋病合并重症肺炎患者病情的控制起到了关键作用。呼吸衰竭患者可给予呼吸机支持治疗及肺保护性通气,以更好地保护和改善肺功能。肠内营养对于该患者的成功救治起到了重要的辅助作用。

关键词: 获得性免疫缺陷综合征, 肺炎

Abstract:

Objective To explore the comprehensive effect of empirical drugs combination in acquired immune deficiency syndrome (AIDS) patients with severe pneumonia opportunistic infection. Methods The one AIDS patients with severe pneumonia admitted to 967 Hospital of the Joint Logistics Support Force of PLA was retrospectively analyzed. The literature review was assessed.Results For the middle-aged men, the history of HIV/AIDS infection were nearly two years, the patient was admitted to hospital due to the weight loss for half a year, 1 month fever cough, increase breathing difficulties with 3 days. After hospitalization, the diagnosis was confirmed: ① severe pneumonia ② TypeⅠ respiratory failure ③ AIDS.The patient was carried out endotracheal intubation and ventilator breathing, with antibiotic therapy, and had enteral nutrition therapy after discharged, 2 months later on court appointment without symptoms of fever, cough, sputum, Reexamination of chest CT showed localized emphysema in the middle lobe of the right lung, absorption of double pneumonia, normal liver function and renal function. Conclusion For AIDS patient with severe pneumonia, the empirical drugs combination plays a key role on the patient's condition without etiological evidence. Ventilator support treatment and pulmonary protective ventilation are better protect and improve lung function, enteral nutrition treatment may contributed to the successful treatment.

Key words: acquired immune deficiency syndrome, pneumonia

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