Clinical Focus ›› 2016, Vol. 31 ›› Issue (1): 77-80.doi: 10.3969/j.issn.1004-583X.2016.01.020

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Risk factors for ischemic cerebral infarction in large-artery atherosclerotic stenosis

Zhang Guangbo1,Yu Kai1, Ji Ruijun1,Wang Yongjun2, Gao Suying1,Yan Yinglin1   

  1. 1. Department of Neurology,Kangji Hospital,Renqiu 062550,China;
    2. Department of Neurology, Beijing Tiantan Hospital,Capital Medical University,Beijing 100050,China
  • Received:2015-09-22 Online:2016-01-05 Published:2016-04-19
  • Contact: Yu Kai, Email:yk_qj@sina.com

Abstract: Objective To investigate the risk factors between ischemic cerebral infarction in large-artery atherosclerotic stenosis and small artery occlusive cerebral infarction.Methods The subjects were based on the standard extract of 736 patients with cerebral infarction. According to the presence of artery stenosis, the patients were divided into two groups: stenosis group(303 cases),non-stenosis group(433 cases). The risk factors between ischemic cerebral infarction with large-artery atherosclerotic stenosis and small artery occlusive cerebral infarction were analyzed.Results After adjusting potential confounders, age (adjusted OR=1.024; 95% CI=1.010-1.039; P<0.01), diabetes (adjusted OR=1.572; 95% CI=1.113-2.219; P=0.010) were shown to be significant associates in schemic cerebral infarction with large-artery atherosclerotic stenosis. High density lipoprotein cholesterol(adjusted OR=0.650; 95% CI=0.432-0.977; P<0.05) was the protection factor of ischemic cerebral infarction in large-artery atherosclerotic stenosis.Conclusion Age, diabetes are independent risk factors for ischemic cerebral infarction in large-artery atherosclerotic stenosis. High density lipoprotein cholesterol is the protection factor.

Key words: infarction,middle cerebral artery, brain infarction, risk factors

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