Abstract: ObjectiveTo evaluate the efficacy of longterm antibiotics combined with inhalation therapy in the treatment of patients with benign tracheal stenosis after bronchoscopic interventional therapy. MethodsRetrospective analysis was performed in the clinical data of 67 cases of benign tracheal stenosis treated with longterm antibiotics （more than 1 month）combined with inhalation of budesonide and amikacin for six months after bronchoscopic interventional therapy. The tracheal diameter and dyspnea index were evaluated before and after bronchoscopic interventional therapy. And initial cure rate and cure rate after six months and complications were evaluated. ResultsAfter bronchoscopic interventional therapy， the tracheal diameter significantly increased from (3.82±0.91) mm to （12.16±1.57) mm(P<0.05)， and the dyspnea index significantly decreased from (3.45±0.63) to (0.52±0.50)(P<0.05). After bronchoscopic interventional therapy， the initial cure rate was 100%. After intravenous antibiotic therapy for one month， combined with inhalation of amikacin and budesonide suspension for six months， the unblocked rate of tracheal was 94.02%. No complications such as double infection happened. ConclusionAfter the bronchoscopic interventional therapy， longterm intravenous antibiotic therapy combined with  inhalation therapy in benign tracheal stenosis can improve longterm  efficacy.

Key words: tracheal stenosis；bronchoscopy；antibacterial , agents