Abstract: Objective  To investigate the risk factors for cognitive impairment in patients with ischemic stroke. Methods  Totally 50 ischemic stroke patients with poststroke cognitive impairment(PSCI) were enrolled as observation group, and another 50 ischemic stroke patients without PSCI were enrolled as control group. The clinical data of these two groups were compared, and the relevant factors of PSCI were analyzed. Results  Compared with the control group, patients in observation group were older; the proportion of complication with hypertension and diabetes were higher; the levels of LDLC, UA and hsCRP were higher; the rate of thalamic infarction and temporal lobe infarction were higher(all P＜0.05).There were statistically significant differences in education levels and stroke frequency between two groups(all P＜0.05). The two or more times of  previous stroke, diabetes, high levels of LDLC and  hsCRP ,and temporal lobe infarction were risk factors for PSCI; while  middle  school or above educational  level  was  the  protective factor for PSCI. Conclusion  Ischemic stroke patients with low educational level, diabetes, previous history stroke, temporal lobe infarction, high levels of LDLC and hsCRP have higher risk for PSCI.

Key words: stroke, cognition disorders, risk factors