Abstract: Objective  To investigate the correlation between preoperative monocytes to highdensity lipoprotein cholesterol ratio(MHR) and contrast  induced nephropathy(CIN) after percutaneous coronary intervention(PCI),to find other possible risk factors for the occurrence of CIN, and to provide a new direction for screening CIN in highrisk groups as early as possible. Methods   Retrospective analysis was made on 1 087 patients with coronary heart disease  who were selected by 5P test and underwent PCI in the department of cardiology of our hospital. They were divided into CIN group and nonCIN group according to whether there was CIN after PCI. The related risk factors of CIN and the correlation between MHR and CIN were studied. Logistic regression analysis was applied to see whether MHR was a risk factor for CIN. Results  There were 57 patients in CIN group and 1 030 patients in nonCIN group. There were statistically significant differences in hyperlipidemia,  BMI, left ventricular ejection fraction (LVEF), preoperative uric acid and preoperative Creactive protein levels between two groups(P<0.05). Logistic regression analysis showed that LVEF and diabetes were correlated with the incidence of CIN. Conclusion  Different from the previous studies, MHR can not be considered as a risk factor for CIN, but LVEF may have higher predictive value for CIN.

Key words: contrast media, nephrosis, angioplasty, transluminal, , percutaneous coronary; , stroke volume