Abstract: Objective  To investigate the features of coronary artery lesions in the youth and elderly patients with suspected coronary artery disease(CAD) using 256slice coronary computed tomography angiograph. Methods  A total of 972 patients with suspected  CAD  undergoing coronary computed tomography angiograph for coronary artery lesions were enrolled.  The patients were divided into youth group (age<60 years,  n=528) and elderly group(age≥60 years,  n=444),  the cardiovascular risk factors and features of coronary artery lesions of two groups were analyzed. Results  The youth group  were higher among gender,  body mass index (BMI),  smoking,  triglyceride than the elderly group; but the prevalence of hypertension was lower than the elderly group(P<0.05). The proportion of calcified plaques and mixed plaques were significantly higher in elderly group than youth group(all P<0.01).  Youth group were mainly singlevessel lesions with low calcification score,  while elderly group were mainly multivessel lesions with high calcification score. Logistic regression analysis indicated that the youthaged degree aggravating the independent risk factors of high coronary artery calcification score were smoking,  hypertension,  diabetes;  while the elderlyaged degree aggravating the independent risk factors of high coronary artery calcification score were diabetes and being male. Conclusion  The characteristics of coronary artery lesions in different age groups have their own clinical features.

Key words: coronary artery lesions, tomography; , spiral , computed, calcification score