Clinical Focus ›› 2023, Vol. 38 ›› Issue (3): 264-267.doi: 10.3969/j.issn.1004-583X.2023.03.013

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One case of neuromyelitis optica with positive antithyroid antibody and literature review

Wang Zijia1,2, Wang Jiuxue2, Wang Tianjun2()   

  1. 1. Graduate School of North China University of Science and Technology,Tangshan 063210,China
    2. Department of Neurology,Hebei General Hospital,Shijiazhuang 050051,China
  • Received:2021-11-11 Online:2023-03-20 Published:2023-05-11
  • Contact: Wang Tianjun E-mail:wangtianj2007@126.com

Abstract:

Objective To investigate the correlation between antithyroid antibodies (ATAbs) and neuromyelitis optica (NMO). Methods The clinical data and antibody detection results of one NMO patient with positive ATAbs were retrospectively analyzed, and the related literatures were reviewed. Results The patient, 61 years old female, left limb numbness for 10 days, aggravation for 3 days. The results of cerebrospinal fluid and serum indicated that aquaporin-4 immunoglobulin G (AQP4-IgG)-positive in cerebrospinal fluid and serum was 1∶1 and 1∶100, respectively. The diagnosis was NMO. Conclusion NMO and thyroid-related diseases are often associated, and more studies are needed to draw definite conclusions about their relationship.

Key words: neuromyelitis optica, thyroid disease, case report

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