Clinical Focus ›› 2015, Vol. 30 ›› Issue (4): 416-420.

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Effect of doxycycline on airway inflammation and remodeling in asthmatic rats

Li Jing;Wang Liang;Yang Hongshen;Li Yamei;Hou Hongwei;Li Xianglan;Zhang Congyao;Li Yujing   

  • Online:2015-04-05 Published:2015-04-05

Abstract: ABSTRACT:Objective To investigate the effect of doxycycline on airway inflammation and remodeling in asthmatic rats.Methods Thirty-three male Sprague Dawley rats were randomly divided into three groups:control group,asthma group and doxycycline interventi

Key words: asthma, airway remodeling, air remodeling, doxycycline, matrix metalloproteinase 9, interleukin-5, interleukin-13, tumor necrosis factor-alpha, actins

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