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Risk factors of nonalcoholic fatty liver disease in males and  value of  body composition analysis

  

  1. Department of Clinical Nutrition,  the Affiliated Hospital of Yangzhou University,   Yangzhou  225000,   China
  • Online:2017-10-05 Published:2017-10-10
  • Contact: Corresponding author: Bao Yun, Email:baoy62@sina.com

Abstract: Objective  To analyze the risk factors of nonalcoholic fatty liver disease (NAFLD) in males and discuss the value of the body composition analysis for evaluating the severity of NAFLD. Methods   A total of 260 male patients diagnosed as NAFLD were  included in the physical examination. According to the diagnosis of ultrasonography, 161 cases were divided into mild group, 65 cases in moderate group, and 34 cases in severe group.In addition,158 healthy male adults without NAFLD served as controls.The changes of body composition were analyzed by  body composition analyzer.Serum was collected to  measure serum lipid,liver and kidney function,ect.Results  Body weight, body mass index (BMI), abdominal perimeter, waist hip ratio, neck circumference, body fat percentage, visceral fat area (VFA), gamma glutamyl transpeptidase (GGT), triglyceride (TG) and high density lipoprotein cholesterol (HDLC) were significantly different between the four groups. Alanine transaminase (ALT), glutamic oxaloacetic transaminase (AST), fasting blood glucose (FBG) and uric acid (UA) of moderate and severe NAFLD patients were significantly higher than those  in control group.  The severity of NAFLD  was  positively correlated to body weight, BMI, abdominal perimeter, waist hip ratio, neck circumference, body fat percentage, VFA, ALT, GGT, TG, FBG and UA. Significant negative correlation was found between the severity of NAFLD and the level of HDLC. FBG and TG were the risk factors of NAFLD. Conclusion  Body composition analysis has a high value in the evaluation of NAFLD.  The risk factors of NAFLD in men were FBG and TG.

Key words: fatty liver;body composition, risk factors