Study advances  of  inflammatory bowel disease complicated with  Clostridium difficile  infection

doi:10.3969/j.issn.1004-583X.2018.05.007

Clinical Focus

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Study advances of inflammatory bowel disease complicated with Clostridium difficile infection

Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of
Medical Science & Peking Union Medical College, Beijing 100730, China

Online:2018-05-05 Published:2018-05-29
Contact: Corresponding author: Qian Jiaming，Email：qianjiaming1957@126.com

Abstract

Abstract: Studies have demonstrated an increasing incidence of Clostridium difficile infection (CDI) in patients with inflammatory bowel disease (IBD). CDI can both precipitate and worsen flares of IBD, contributing to emergent colectomies and mortality. Host microbiome, immune response and genetics jointly decide whether patients with IBD will suffer from CDI. Further studies may help define pathogenesis of CDI as well as identify high risk subgroups that may benefit from prophylactic intervention.

Key words: inflammatory bowel disease, Clostridium , infections; , intestinal microbiome, genetics

Li Yue, Qian Jiaming. Study advances of inflammatory bowel disease complicated with Clostridium difficile infection[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2018.05.007.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2018.05.007

https://huicui.hebmu.edu.cn/EN/Y2018/V33/I5/394

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Study advances of inflammatory bowel disease complicated with Clostridium difficile infection

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