Magnetic resonance imaging characteristics of Andersson lesions associated with ankylosing spondylitis

doi:10.3969/j.issn.1004-583X.2022.10.008

Abstract

Abstract:

Objective To investigate the magnetic resonance imaging (MRI) characteristics of Anderson lesions (AL) associated with ankylosing spondylitis (AS). Methods A retrospective analysis was made on 78 AS patients who underwent spinal MRI examination in the Department of Radiology, Harbin Institute of Technology Hospital from July 2018 to November 2021, and in the Department of MRI, the 2nd Affiliated Hospital of Harbin Medical University from January 2018 to November 2021.The clinical data were compared in two groups which comprised 23 (inflammatory group) and 10 (traumatic group) patients. Results Among 78 AS patients, 33 had AL, with a detection rate of 42.3%. The modified Stoke ankylosing spondylitis spine score (mSASSS) in traumatic group was higher than that in inflammatory group (P<0.05). The difference of involved discovertebral units (DVUs) between the two groups was statistically significant (P<0.05), and the MRI characteristics were different. Correlation analysis showed that erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), human leucocyte antigen-B27 (HLA-B27), Bath ankylosing spondylitis disease activity index (BASDAI), mSASSS were not correlated with the number of involved DVUs(P>0.05). Conclusion AL is not rare in AS patients. Inflammatory AL and traumatic AL have different MRI manifestations. MRI has important value in detecting and evaluating AL.

Key words: ankylosing spondylitis, Andersson lesions, magnetic resonance imaging

CLC Number:

R593.23

Gao Ying, Han Zhongli, Wang Hongyan, Li Xiaofu. Magnetic resonance imaging characteristics of Andersson lesions associated with ankylosing spondylitis[J]. Clinical Focus, 2022, 37(10): 927-930.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2022.10.008

https://huicui.hebmu.edu.cn/EN/Y2022/V37/I10/927

Figures/Tables 4

References 21

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机器型号	重复时间(ms)	回波时间(ms)	层厚(mm)	视野(mm)	矩阵
飞利浦1.5T
T1WI	253~538	8~10	5	280×280	576×576
T2WI	1 395~2 573	84~120	5	264×264	528×528
T2WI-FS	1 455~2 350	84~120	5	264×264	528×528
西门子1.5T
T1WI	400~756	9.7~11	4	306×384	512×512
T2WI	2 020~3 830	99~104	4	384×384	512×512
T2WI-FS	2 160~2 500	99~104	4	384×384	512×512

机器型号	重复时间(ms)	回波时间(ms)	层厚(mm)	视野(mm)	矩阵
飞利浦1.5T
T1WI	253~538	8~10	5	280×280	576×576
T2WI	1 395~2 573	84~120	5	264×264	528×528
T2WI-FS	1 455~2 350	84~120	5	264×264	528×528
西门子1.5T
T1WI	400~756	9.7~11	4	306×384	512×512
T2WI	2 020~3 830	99~104	4	384×384	512×512
T2WI-FS	2 160~2 500	99~104	4	384×384	512×512

组别	例数	年龄(岁)	性别[例(%)]		病程(年)	ESR(mm/hr)	CRP(mg/dl)	HLA-B27		mSASSS(分)	BASDAI(分)
组别	例数	年龄(岁)	男	女	病程(年)	ESR(mm/hr)	CRP(mg/dl)	阳性	阴性	mSASSS(分)	BASDAI(分)
炎症型	23	34.96±7.37	13(56.5)	10(43.5)	4.35±1.23	24.25±12.38	1.53±0.40	21(91.3)	2(0.7)	15.35±3.65	4.03±0.62
创伤型	10	41.20±6.37	6(60.0)	4(40.0)	5.80±0.79	26.55±13.88	1.60±0.35	10(100.0)	0	35.32±4.50	4.21±1.06
统计值		t=2.322			t=3.426	t=0.473	t=0.444			t=9.316	t=0.630
P值		>0.05	>0.05		>0.05	>0.05	>0.05	>0.05		0.000	>0.05

组别	例数	年龄(岁)	性别[例(%)]		病程(年)	ESR(mm/hr)	CRP(mg/dl)	HLA-B27		mSASSS(分)	BASDAI(分)
组别	例数	年龄(岁)	男	女	病程(年)	ESR(mm/hr)	CRP(mg/dl)	阳性	阴性	mSASSS(分)	BASDAI(分)
炎症型	23	34.96±7.37	13(56.5)	10(43.5)	4.35±1.23	24.25±12.38	1.53±0.40	21(91.3)	2(0.7)	15.35±3.65	4.03±0.62
创伤型	10	41.20±6.37	6(60.0)	4(40.0)	5.80±0.79	26.55±13.88	1.60±0.35	10(100.0)	0	35.32±4.50	4.21±1.06
统计值		t=2.322			t=3.426	t=0.473	t=0.444			t=9.316	t=0.630
P值		>0.05	>0.05		>0.05	>0.05	>0.05	>0.05		0.000	>0.05

组别	受累 DVUs 数量	颈椎受累 DVUs (C1-C7)	上胸椎受累 DVUs (T1-T9)	胸腰段受累 DVUs (T10-L2)	下腰椎受累 DVUs (L3-L5)
炎症型	32	4(12.5)	6(18.8)	15(46.9)	7(21.8)
创伤型	10	0	0	7(70.0)	3(30.0)
χ²值		19.528
P值		0.000