Clinical Focus ›› 2016, Vol. 31 ›› Issue (2): 187-190.doi: 10.3969/j.issn.1004-583X.2016.02.012

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Clinical efficacy and language recovery of butylphthalide injection in aphasia patients with cerebral infarction

Wu Xiaona, Liu Yan, Xiang Wei, Xiong Tiegen, Li Chunyong,Deng Wenting   

  1. Neuromedical Special Hospital, Guangzhou General Hospital of Guangzhou Command, Guangzhou 510010, China
  • Received:2016-01-20 Online:2016-02-05 Published:2016-04-18
  • Contact: Wu Xiaona,Email:13889904009@139.com

Abstract: Objective To study the clinical efficacy of butylphthalide injection and the language recovery in aphasia patients with cerebral infarction.Methods Twenty-six aphasia patients with acute cerebral infarction were randomly divided into two groups, treatment and control. Both groups were treated with anti-platelet and basic therapy conventionally, but the treatment group was treated with butylphthalide injection, 100 ml, intravenously, 1/12 h for (11± 3) d. NIHSS and AQ were recorded before and after treatment.Results Before treatment,the gender, age, onset time, NIHSS score and complications of the patients,such as hypertension, diabetes, hyperlipidemia in two groups had no significant difference (P>0.05). After treatment, the scores of NIHSS decreased in two groups (P<0.01). However, the score of treatment group decreased significantly compared with that of control group (P<0.05). The clinical efficacy and the improvement of AQ were significantly better than those of control group (P<0.05).Conclusion Butylphthalide injection in the treatment of aphasia patients with cerebral infarction can improve the clinical function effectively and promote the recovery of language function injury at the same time, it also has a high security in clinical application.

Key words: brain infarction, aphasia, butylphthalide injection

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