Association between serum triiodothyronine level and coronary artery disease  in elderly patients with low triiodothvronine syndrome

doi:10.3969/j.issn.1004-583X.2017.03.009

Abstract

Abstract: ObjectiveTo investigate coronary artery lesion in elderly patients with coronary artery disease(CAD) combined with low three triiodothyronine(T3）syndrome，and the correlation between T3 serum hormone levels and coronary artery lesion. MethodsA total of 275 elderly CAD patients with low T3 syndrome served as group A，275 elderly CAD patients with normal free triiodothyronine（FT3），free thyroxine（FT4），thyroid stimulating hormone （TSH） were selected as group B（control group）. FT3，FT4 and TSH in two groups were determined. CAD was evaluated by lesion count and Gensini score was calculated according to the results of coronary arteriongraphy. ResultsTotal cholesterol and LDLC were higher in group A than in group B（P<0.05）.Serum FT3 in group A was lower than in group B（P<0.05）.Gensini score in group A was higher than in group B(P<0.05).As the characteristics of coronary artery lesion，three vessels disease incidence was higher in group A than in group B（P<0.05）.In group A，severe coronary artery stenosis and complete occlusion were higher compared with those in group B（P<0.05）.Multivariate logistic regression analysis showed that low FT3 was related to number and degree of coronary artery lesions. ConclusionThe lesion of CAD in the elderly patients with low T3 syndrome are mainly multivessel and twovessel lesion involving a wide range and higher severity.

Key words: coronary artery disease, triiodothyronine, thyroxine

Du Ronggui. Association between serum triiodothyronine level and coronary artery disease in elderly patients with low triiodothvronine syndrome[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2017.03.009.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2017.03.009

https://huicui.hebmu.edu.cn/EN/Y2017/V32/I3/216

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Association between serum triiodothyronine level and coronary artery disease in elderly patients with low triiodothvronine syndrome

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