临床荟萃

• 论著 • 上一篇    下一篇

107例次恶性肿瘤患者深静脉导管相关性血流感染情况分析及预防对策

  

  1. 1.芜湖市第一人民医院 a.肿瘤科; b.院感科,安徽 芜湖 241000; 2. 安徽中医药大学第二附属医院 肿瘤内科,安徽 合肥 230000; 
    3.安阳地区医院 肿瘤内科,河南 安阳  457000
  • 出版日期:2017-08-05 发布日期:2017-08-10
  • 通讯作者: 通信作者:程晓健,Email: 13675845017@163.com
  • 基金资助:
    安徽中医药大学青年科学研究基金(2014qn033)

Analysis and prevention of deep venous catheter related bloodstream infection in 107 patients with malignant tumor

  1. 1a.Department of Oncology; 1b. Department of Infection Control,  Wuhu No1 People's Hospital, Wuhu 241000,China;
    2.Department of Oncology, the Second Affiliated Hospital of Anhui Medical University, Hefei 230000,China;
    3.Department of Oncology, Anyang District Hospital, Anyang 457000,China
  • Online:2017-08-05 Published:2017-08-10
  • Contact: Corresponding author: Cheng Xiaojian,Email: 13675845017@163.com

摘要: 目的  通过回顾性分析恶性肿瘤患者深静脉导管相关性血流感染情况,为临床防治该类患者提供参考。方法 回顾性分析芜湖市第一人民医院、安徽中医药大学第二附属医院、安阳地区医院2014年1月至2016年12月共107例次恶性肿瘤患者发生的深静脉导管相关性血流感染情况及病原学结果。结果 107例次深静脉导管感染,其中培养出革兰阳性菌46例(42.98%),革兰阴性菌38例(35.51%),真菌23例(21.51%);其中导管留置后在7~30天内出现的感染率最高,达43.90%;不同的导管维护方式的经外用静脉导入中心静脉置管(PICC)导管感染情况亦不同,个体诊所、外院维护和自行维护的感染例数的构成比分别达到48.7%和28.3%。结论 恶性肿瘤患者深静脉导管相关性血流感染主要以革兰阳性菌为主,导管留置后在7~30天内出现的感染率最高,应加强预防,不正确的维护方式将导致相关性血流感染率明显增高。

关键词: 癌, 导管插入术, 细菌感染

Abstract: Objective  To analyze deep venous catheterrelated bloodstream infection in patients with malignant tumor for reference in prevention and treatment of the disease. Methods  Retrospective analysis was made in 107 cases of patients with malignant tumor in the hospital from January 2014 to December 2016, including the incidence of deep venous catheterrelated bloodstream infection. Results  In 107 patients  of  deep venous catheter related bloodstream infection,gram positive bacteria were cultured in 46 cases (42.98%), gram negative bacteria 38 cases (35.51%) and fungi 23 cases (21.51%). The highest infection rate was found in 730 days after catheter indwelling, up to 43.90%. The ways of catheter maintenance of peripherally inserted central catheters (PICC) infection  also showed significant difference. The constituent ratios of two PICC infections from individual clinics or/ external hospitals maintenance and self maintenances were respectively 48.7% and 28.3%. Conclusion  Malignant tumor patients with deep venous catheterrelated bloodstream infection were mainly gram positive bacteria. The highest infection rate was found in 730 days after catheter indwelling. Prevention should be strengthened. Improper maintenance will result in a significant increase in the rate of infection.

Key words: carcinoma, catheterization, bacterial infections