临床荟萃

• 论著 • 上一篇    下一篇

以腹痛为首发症状的儿童过敏性紫癜的危险因素分析

  

  1. 福建省妇幼保健院 福建医科大学附属医院  儿科,福建 福州 350001
  • 出版日期:2020-10-20 发布日期:2020-09-04
  • 通讯作者: 通信作者:叶红,Email:1013379025@qq.com

Risk factors  for  HenochSchonlein Purpura in children with abdominal pain as initial symptom

  1. Department of Pediatrics,  Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou 350001, China
  • Online:2020-10-20 Published:2020-09-04
  • Contact: Corresponding author:Ye Hong,Email:1013379025@qq.com

摘要: 目的  分析以腹痛为首发症状的儿童过敏性紫癜的临床特点,探讨其危险因素。方法  纳入腹型过敏性紫癜共168例,根据是否以腹痛为首发症状,分为病例组55例和对照组113例,病例组为以腹痛为首发症状,对照组为皮疹先于腹痛出现的腹型过敏性紫癜患儿。探讨以腹痛为首发症状的儿童过敏性紫癜的独立危险因素。结果  在168例儿童腹型过敏性紫癜中,以腹痛为首发症状占比高达32.7%(55/168),皮疹滞后于腹痛出现的时间范围为1~20天。两组间粪便隐血试验、入院体重、白细胞计数、血小板计数、总蛋白、白蛋白、D二聚体差别有统计学意义;Logistic回归模型分析显示:D二聚体是以腹痛为首发症状的过敏性紫癜患儿的独立危险因素。 结论  对于腹痛合并D二聚体升高的儿童,需警惕腹型过敏性紫癜的可能。D二聚体对以腹痛为首发症状的过敏性紫癜的早期诊断有一定的参考价值。

关键词: 紫癜, 过敏性, 腹痛, 儿童

Abstract: Objective  To analyze the clinical characteristics of HenochSchonlein Purpura (HSP) in children with abdominal pain as initial symptom, to explore its associated risk factors. Methods  A total of 168 cases of abdominal type of HSP were included.According to whether abdominal pain  was the initial symptom,  they were divided into case group 55 cases and control group 113 cases. In  case group, abdominal pain was the  initial symptom, while in control group, skin rash appeared before abdominal pain. The independent risk factors of HSP  in children with abdominal pain as the initial symptom were explored. Results  In 168 cases of  children with abdominal  HSP,  abdominal pain as the initial symptom accounted for  32.7%(55/168). The rash lagged  behind the onset of abdominal pain for a time range of 1 to 20 days. Significant differences between two groups included fecal occult blood test, admission  body  weight, leukocyte count, platelet count, total protein, albumin and Ddimer. Logistic regression model analysis showed that Ddimer  was  an independent risk factor for HSP children with abdominal pain as initial symptom. Conclusion  For children  with abdominal pain and increased Ddimer, the possibility of  abdominal  HSP should be warned. Ddimer has certain reference value for the  early diagnosis of HSP with abdominal pain as initial symptom.

Key words: purpura, schoenleinhenoch, abdominal pain, children