临床荟萃 ›› 2014, Vol. 29 ›› Issue (6): 648-650.

• 论文 • 上一篇    下一篇

高通量血液透析联合促红细胞生成素治疗维持性肾性贫血的临床评价

高连彬;黄红丽;黎明;成亚珍;李媛;田勇武   

  1. 定州市人民医院 肾内科,河北 定州,073000
  • 出版日期:2014-06-05 发布日期:2014-06-05

Clinical evaluation on high-flux hemodialysis jointed with erythropoietin treatment in maintenance renal anemia

GAO Lian-bin;HUANG Hong-li;LI Ming;CHENG Ya-zhen;LI Yuan;TIAN Yong-wu   

  • Online:2014-06-05 Published:2014-06-05

摘要: 目的:探讨高通量血液透析联合促红细胞生成素(EPO)治疗维持性肾性贫血的临床效果。方法肾性贫血患者30例,随机分为治疗组和对照组各15例,分别用高通量血液透析联合 EPO 治疗和低通量血液透析联合EPO治疗,疗程1年,观察两组的疗效。结果治疗组的不良反应率小于对照组(6.4% vs 66.7%,P <0.05);治疗后与对照组比较,治疗组的尿素氮(BUN)、血细胞比容(Hct)明显下降,分别为(2.1±0.5)mmol/L vs (1.1±0.2) mmol/L(P<0.01)及(152.6±119.1)% vs (38.8±17.2)%(P <0.01),而与对照组比较,治疗组的多效蛋白(PTN)和血红蛋白(Hb)明显升高,分别为(100.6±3.8)mg/L vs (57.0±1.5)mg/L(P<0.05)及(31.1±0.5)g/L vs (18.7±0.5)g/L(P<0.01)。结论高通量血液透析联合 EPO治疗维持性肾性贫血临床效果好、安全高。

关键词: 肝静脉血栓形成, 门静脉, 体层摄影术

Abstract: Objective To investigate the high-flux hemodialysis jointed with erythropoietin therapy to maintain clinical effects of renal anemia.Methods Thirty cases of renal anemia were randomly divided into treatment group and control group,1 5 cases,respectively i

Key words: kidney failure;chronic, anemia, renal dialysis, erythropoietin, clinical evaluation

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