临床荟萃

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炎性关节病与骨质疏松

  

  1. 北京积水潭医院 风湿免疫科,北京 100035
  • 出版日期:2019-04-20 发布日期:2019-05-16
  • 通讯作者: 宋慧,Email:jst_fsmy@163.com
  • 作者简介:宋慧,北京积水潭医院风湿免疫科主任。中华医学会风湿免疫分会第十届委员;北京医学会风湿免疫分会常委;北京大学医学部风湿免疫学学系副主任;中国医师协会风湿免疫科医师分会委员及痛风专业委员会委员;海峡两岸医药卫生交流协会风湿免疫病学专家委员及痛风学组常委;Committee member of AsiaPacific Consortium;海协会风湿免疫病学专家委员及骨关节炎学组常委。
  • 基金资助:
    “十三五”国家重点研发计划精准医学项目----类风湿关节炎的临床队列及预后研究(2017YFC0907604)

Inflammatory arthropathy and osteoporosis

  1. Department of Rheumatology and Immunology,  Beijing Jishuitan Hospital,  Beijing 100035, China
  • Online:2019-04-20 Published:2019-05-16
  • Contact: Corresponding author: Song Hui, Email:jst_fsmy@163.com

摘要: 炎性关节病是以关节炎为主要表现的一组疾病,包括类风湿关节炎、脊柱关节炎、骨关节炎等。骨质疏松分为原发性和继发性,炎性关节病是继发性骨质疏松的常见原因。炎性关节病合并骨质疏松概率增加,因同时存在关节障碍使跌倒风险升高,故一旦合并骨质疏松,骨折风险会明显加大,值得临床医师重视。对此类患者需尽早筛查骨密度,一旦合并骨质疏松,应积极进行干预以降低骨折风险,改善预后。本文就炎性关节病与骨质疏松的流行病学、发病机制及诊治进展做一综述。

关键词: 关节炎, 类风湿;脊柱炎;骨关节炎;骨质疏松

Abstract: Inflammatory arthropathy is a group of diseases characterized by arthritis,  mainly  including rheumatoid arthritis,  spondyloarthritis and osteoarthritis.Osteoporosis is divided into primary and secondary types. Inflammatory arthropathy is a common cause of secondary osteoporosis.The incidence of osteoporosis and the risk of falls increase in inflammatory arthropathy. Therefore,  once osteoporosis appears,  the risk of fracture will increase significantly.Bone mineral density should be screened as soon as possible in patients with inflammatory arthropathy.Once osteoporosis is diagnosed,  treatment should be initiated to reduce the risk of fracture and improve the prognosis. The epidemiology and pathogenesis of inflammatory arthropathy and osteoporosis and their diagnosis as well as treatment were reviewed in this paper.

Key words: arthritis, , rheumatoid, spondylitis, osteoarthritis, osteopo