临床荟萃 ›› 2024, Vol. 39 ›› Issue (4): 357-362.doi: 10.3969/j.issn.1004-583X.2024.04.011
徐孟丹1, 王礼琳2(
)
收稿日期:2023-08-25
出版日期:2024-04-20
发布日期:2024-06-28
通讯作者:
王礼琳,Email:
Received:2023-08-25
Online:2024-04-20
Published:2024-06-28
摘要：
缺血性心肌病是一种常见的心肌病类型,是冠心病的一种特殊类型或晚期阶段,可引起心力衰竭、心律失常。阻塞性睡眠呼吸暂停是缺血性心肌病的可逆危险因素之一,通过内皮功能损害等病理生理机制导致冠状动脉粥样硬化、心力衰竭、心律失常等。缺血性心肌病伴阻塞性睡眠呼吸暂停患者可通过持续气道正压通气等治疗改善其预后。现将阻塞性睡眠呼吸暂停与缺血性心肌病中冠状动脉粥样硬化、心力衰竭和心律失常的发病机制及治疗阻塞性睡眠呼吸暂停对缺血性心肌病的影响综述如下。
中图分类号:
徐孟丹, 王礼琳. 阻塞性睡眠呼吸暂停与缺血性心肌病的关系研究进展[J]. 临床荟萃, 2024, 39(4): 357-362.
| [1] |
Karantalis V, Suncion-Loescher VY, Bagno L, et al. Synergistic effects of combined cell therapy for chronic ischemic cardiomyopathy[J]. J Am Coll Cardiol, 2015, 66 (18):1990-1999.
doi: S0735-1097(15)06092-1 pmid: 26516002 |
| [2] | Kahle AK, Jungen C, Alken FA, et al. Management of ventricular tachycardia in patients with ischaemic cardiomyopathy: Contemporary armamentarium[J]. Europace, 2022, 24(4):538-551. |
| [3] |
Proietti R, Labos C, Davis M, et al. A systematic review and meta-analysis of the association between implantable cardioverter-defibrillator shocks and long-term mortality[J]. Can J Cardiol, 2015, 31(3):270-277.
doi: 10.1016/j.cjca.2014.11.023 pmid: 25746019 |
| [4] |
Rog-Zielinska EA, Norris RA, Kohl P, et al. The living scar--cardiac fibroblasts and the injured heart[J]. Trends Mol Med, 2016, 22(2):99-114.
doi: S1471-4914(15)00236-1 pmid: 26776094 |
| [5] |
Somers VK, White DP, Amin R, et al. Sleep apnea and cardiovascular disease: An american heart association/american college of cardiology foundation scientific statement from the american heart association council for high blood pressure research professional education committee, council on clinical cardiology, stroke council, and council on cardiovascular nursing. In collaboration with the national heart, lung, and blood institute national center on sleep disorders research (national institutes of health)[J]. Circulation, 2008, 118(10):1080-1111.
doi: 10.1161/CIRCULATIONAHA.107.189375 pmid: 18725495 |
| [6] |
Peppard PE, Young T, Barnet JH, et al. Increased prevalence of sleep-disordered breathing in adults[J]. Am J Epidemiol, 2013, 177(9):1006-1014.
doi: 10.1093/aje/kws342 pmid: 23589584 |
| [7] |
Faria A, Allen AH, Fox N, et al. The public health burden of obstructive sleep apnea[J]. Sleep Sci, 2021, 14(3):257-265.
doi: 10.5935/1984-0063.20200111 pmid: 35186204 |
| [8] | No authors listed. Sleep-related breathing disorders in adults: Recommendations for syndrome definition and measurement techniques in clinical research[J]. Sleep, 1999, 22(5):667-689. |
| [9] |
Myers KA, Mrkobrada M, Simel DL. Does this patient have obstructive sleep apnea?: The rational clinical examination systematic review[J]. JAMA, 2013, 310 (7):731-741.
doi: 10.1001/jama.2013.276185 pmid: 23989984 |
| [10] | Venkataraman S, Vungarala S, Covassin N, et al. Sleep apnea, hypertension and the sympathetic nervous system in the adult population[J]. J Clin Med, 2020, 9 (2):591. |
| [11] | Lee CH, Khoo SM, Chan MY, et al. Severe obstructive sleep apnea and outcomes following myocardial infarction[J]. J Clin Sleep Med, 2011, 7(6):616-621. |
| [12] |
Stevenson IH, Roberts-Thomson KC, Kistler PM, et al. Atrial electrophysiology is altered by acute hypercapnia but not hypoxemia: Implications for promotion of atrial fibrillation in pulmonary disease and sleep apnea[J]. Heart Rhythm, 2010, 7(9):1263-1270.
doi: 10.1016/j.hrthm.2010.03.020 pmid: 20338265 |
| [13] |
Linz D, Schotten U, Neuberger HR, et al. Negative tracheal pressure during obstructive respiratory events promotes atrial fibrillation by vagal activation[J]. Heart Rhythm, 2011, 8(9):1436-1443.
doi: 10.1016/j.hrthm.2011.03.053 pmid: 21457790 |
| [14] |
Priori SG, Blomström-Lundqvist C, Mazzanti A, et al. 2015 ESC guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: The task force for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death of the european society of cardiology (ESC). Endorsed by: Association for european paediatric and congenital cardiology (AEPC)[J]. Eur Heart J, 2015, 36(41):2793-2867.
doi: 10.1093/eurheartj/ehv316 pmid: 26320108 |
| [15] | Xie J, Sert Kuniyoshi FH, Covassin N, et al. Nocturnal hypoxemia due to obstructive sleep apnea is an independent predictor of poor prognosis after myocardial infarction[J]. J Am Heart Assoc, 2016, 5(8):e003162. |
| [16] | Xie J, Sert Kuniyoshi FH, Covassin N, et al. Excessive daytime sleepiness independently predicts increased cardiovascular risk after myocardial infarction[J]. J Am Heart Assoc, 2018, 7(2):e007221. |
| [17] |
Marin JM, Carrizo SJ, Vicente E, et al. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: An observational study[J]. Lancet, 2005, 365 (9464):1046-1053.
doi: 10.1016/S0140-6736(05)71141-7 pmid: 15781100 |
| [18] |
Bradley TD, Floras JS. Obstructive sleep apnoea and its cardiovascular consequences[J]. Lancet, 2009, 373(9657):82-93.
doi: 10.1016/S0140-6736(08)61622-0 pmid: 19101028 |
| [19] | Lee CH, Sethi R, Li R, et al. Obstructive sleep apnea and cardiovascular events after percutaneous coronary intervention[J]. Circulation, 2016, 133(21):2008-2017. |
| [20] |
Javaheri S, Barbe F, Campos-Rodriguez F, et al. Sleep apnea: Types, mechanisms, and clinical cardiovascular consequences[J]. J Am Coll Cardiol, 2017, 69(7):841-858.
doi: S0735-1097(17)30009-8 pmid: 28209226 |
| [21] |
Celermajer DS. Reliable endothelial function testing: At our fingertips?[J] Circulation, 2008, 117(19):2428-2430.
doi: 10.1161/CIRCULATIONAHA.108.775155 pmid: 18474821 |
| [22] |
Williams B, Mancia G, Spiering W, et al. 2018 ESC/ESH guidelines for the management of arterial hypertension: The task force for the management of arterial hypertension of the european society of cardiology and the european society of hypertension: The task force for the management of arterial hypertension of the european society of cardiology and the european society of hypertension[J]. J Hypertens, 2018, 36(10):1953-2041.
doi: 10.1097/HJH.0000000000001940 pmid: 30234752 |
| [23] |
Shpilsky D, Erqou S, Patel SR, et al. Association of obstructive sleep apnea with microvascular endothelial dysfunction and subclinical coronary artery disease in a community-based population[J]. Vasc Med, 2018, 23(4):331-339.
doi: 10.1177/1358863X18755003 pmid: 29537350 |
| [24] | Stumpf MJ, Schaefer CA, Krycki J, et al. Impairment of vascular strain in patients with obstructive sleep apnea[J]. PLoS One, 2018, 13(2):e0193397. |
| [25] | Caballero-Eraso C, Muñoz-Hernández R, Asensio Cruz MI, et al. Relationship between the endothelial dysfunction and the expression of the β1-subunit of BK channels in a non-hypertensive sleep apnea group[J]. PloS One, 2019, 14(6):e0217138. |
| [26] | Wang Y, Xu H, Qian Y, et al. Patients with obstructive sleep apnea display decreased flow-mediated dilatation: Evidence from a meta-analysis[J]. Med Sci Monit, 2017, 23(10):1069-1082. |
| [27] | Wang J, Yu W, Gao M, et al. Impact of obstructive sleep apnea syndrome on endothelial function, arterial stiffening, and serum inflammatory markers: An updated meta-analysis and metaregression of 18 studies[J]. J Am Heart Assoc, 2015, 4(11):e002454. |
| [28] | Kyotani Y, Takasawa S, Yoshizumi M. Proliferative pathways of vascular smooth muscle cells in response to intermittent hypoxia[J]. Int J Mol Sci, 2019, 20(11):2706. |
| [29] | Matsuura Y, Yamashita A, Iwakiri T, et al. Vascular wall hypoxia promotes arterial thrombus formation via augmentation of vascular thrombogenicity[J]. Thromb Haemost, 2015, 114(1):158-172. |
| [30] | Kaczmarek E, Bakker JP, Clarke DN, et al. Molecular biomarkers of vascular dysfunction in obstructive sleep apnea[J]. PLoS One, 2013, 8(7):e70559. |
| [31] |
Seif F, Patel SR, Walia H, et al. Association between obstructive sleep apnea severity and endothelial dysfunction in an increased background of cardiovascular burden[J]. J Sleep Res, 2013, 22(4):443-451.
doi: 10.1111/jsr.12026 pmid: 23331757 |
| [32] | Ochijewicz D, Rdzanek A, Przybyłowski T, et al. Influence of apnea hypopnea index and the degree of airflow limitation on endothelial function in patients un-dergoing diagnostic coronary angiography[J]. Biology (Basel), 2022, 11 (3):457. |
| [33] |
Wang T, Yu FC, Wei Q, et al. Sleep-disordered breathing in heart failure patients with different etiologies[J]. Clin Cardiol, 2022, 45(7):778-785.
doi: 10.1002/clc.23840 pmid: 35535628 |
| [34] | Salama S, Omar A, Ahmed Y, et al. Sleep-disordered breathing in ischemic cardiomyopathy and hypertensive heart failure patients[J]. Egyptian J Bronchol, 2017, 11(2):154-160. |
| [35] |
Prinz C, Bitter T, Piper C, et al. Sleep apnea is common in patients with coronary artery disease[J]. Wien Med Wochenschr, 2010, 160(13-14):349-355.
doi: 10.1007/s10354-009-0737-x pmid: 20694765 |
| [36] |
Deegan PC, McNicholas WT. Pathophysiology of obstructive sleep apnoea[J]. Eur Respir J, 1995, 8(7):1161-1178.
doi: 10.1183/09031936.95.08071161 pmid: 7589402 |
| [37] | Nicholl DD, Hanly PJ, Poulin MJ, et al. Evaluation of continuous positive airway pressure therapy on renin-angiotensin system activity in obstructive sleep apnea[J]. Am J Respir Crit Care Med, 2014, 190(5):572-580. |
| [38] |
Arzt M, Young T, Finn L, et al. Sleepiness and sleep in patients with both systolic heart failure and obstructive sleep apnea[J]. Arch Intern Med, 2006, 166 (16):1716-1722.
pmid: 16983049 |
| [39] |
Wachter R, Lüthje L, Klemmstein D, et al. Impact of obstructive sleep apnoea on diastolic function[J]. Eur Respir J, 2013, 41(2):376-383.
doi: 10.1183/09031936.00218211 pmid: 22790918 |
| [40] |
Gottlieb DJ, Yenokyan G, Newman AB, et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: The sleep heart health study[J]. Circulation, 2010, 122(4):352-360.
doi: 10.1161/CIRCULATIONAHA.109.901801 pmid: 20625114 |
| [41] |
Wang H, Parker JD, Newton GE, et al. Influence of obstructive sleep apnea on mortality in patients with heart failure[J]. J Am Coll Cardiol, 2007, 49(15):1625-1631.
doi: S0735-1097(07)00436-6 pmid: 17433953 |
| [42] |
Khayat R, Jarjoura D, Porter K, et al. Sleep disordered breathing and post-discharge mortality in patients with acute heart failure[J]. Eur Heart J, 2015, 36(23):1463-1469.
doi: 10.1093/eurheartj/ehu522 pmid: 25636743 |
| [43] |
May AM, Van Wagoner DR, Mehra R. OSA and cardiac arrhythmogenesis: Mechanistic insights[J]. Chest, 2017, 151(1):225-241.
doi: S0012-3692(16)59256-3 pmid: 27693594 |
| [44] |
Leung RS. Sleep-disordered breathing: Autonomic mechanisms and arrhythmias[J]. Prog Cardiovasc Dis, 2009, 51(4):324-338.
doi: 10.1016/j.pcad.2008.06.002 pmid: 19110134 |
| [45] |
Drager LF, Bortolotto LA, Figueiredo AC, et al. Obstructive sleep apnea, hypertension, and their interaction on arterial stiffness and heart remodeling[J]. Chest, 2007, 131(5):1379-1386.
pmid: 17494787 |
| [46] |
Gami AS, Hodge DO, Herges RM, et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation[J]. J Am Coll Cardiol, 2007, 49(5):565-571.
doi: 10.1016/j.jacc.2006.08.060 pmid: 17276180 |
| [47] |
Burstein B, Nattel S. Atrial fibrosis: Mechanisms and clinical relevance in atrial fibrillation[J]. J Am Coll Cardiol, 2008, 51(8):802-809.
doi: 10.1016/j.jacc.2007.09.064 pmid: 18294563 |
| [48] |
Hindricks G, Potpara T, Dagres N, et al. 2020 ESC guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the european association for cardio-thoracic surgery (EACTS): The task force for the diagnosis and management of atrial fibrillation of the european society of cardiology (ESC) developed with the special contribution of the european heart rhythm association (EHRA) of the ESC[J]. Eur Heart J, 2021, 42(5):373-498.
doi: 10.1093/eurheartj/ehaa612 pmid: 32860505 |
| [49] |
Olmetti F, La Rovere MT, Robbi E, et al. Nocturnal cardiac arrhythmia in patients with obstructive sleep apnea[J]. Sleep Med, 2008, 9(5):475-480.
pmid: 18024169 |
| [50] |
Navarro-Antolín J, Carmona-Bernal C, Rivero-Valdenebro V, et al. Maxi-K+ channel beta1 expression in sleep apnea patients and its modulation by CPAP treatment[J]. Am J Hypertens, 2009, 22(2):197-202.
doi: 10.1038/ajh.2008.342 pmid: 19057512 |
| [51] |
Bayram NA, Ciftci B, Keles T, et al. Endothelial function in normotensive men with obstructive sleep apnea before and 6 months after CPAP treatment[J]. Sleep, 2009, 32(10):1257-1263.
doi: 10.1093/sleep/32.10.1257 pmid: 19848355 |
| [52] | Pamidi S, Wroblewski K, Stepien M, et al. Eight hours of nightly continuous positive airway pressure treatment of obstructive sleep apnea improves glucose metabolism in patients with prediabetes. A randomized controlled trial[J]. Am J Respir Crit Care Med, 2015, 192(1):96-105. |
| [53] |
Bratton DJ, Stradling JR, Barbé F, et al. Effect of CPAP on blood pressure in patients with minimally symptomatic obstructive sleep apnoea: A meta-analysis using individual patient data from four randomised controlled trials[J]. Thorax, 2014, 69(12):1128-1135.
doi: 10.1136/thoraxjnl-2013-204993 pmid: 24947425 |
| [54] |
Arias MA, García-Río F, Alonso-Fernández A, et al. Pulmonary hypertension in obstructive sleep apnoea: Effects of continuous positive airway pressure: A randomized, controlled cross-over study[J]. Eur Heart J, 2006, 27(9):1106-1113.
pmid: 16497687 |
| [55] |
Qureshi WT, Nasir UB, Alqalyoobi S, et al. Meta-analysis of continuous positive airway pressure as a therapy of atrial fibrillation in obstructive sleep apnea[J]. Am J Cardiol, 2015, 116(11):1767-1773.
doi: 10.1016/j.amjcard.2015.08.046 pmid: 26482182 |
| [56] | McEvoy RD, Antic NA, Heeley E, et al. CPAP for prevention of cardiovascular events in obstructive sleep apnea[J]. N Engl J Med, 2016, 375(10):919-931. |
| [57] | Seyis S, Usalan AK, Rencuzogullari I, et al. The effects of continuous positive airway pressure on premature ventricular contractions and ventricular wall stress in patients with heart failure and sleep apnea[J]. Can Respir J, 2018, 2018(2):2027061. |
| [58] | Lee CH, Khoo SM, Tai BC, et al. Obstructive sleep apnea in patients admitted for acute myocardial infarction. Prevalence, predictors, and effect on microvascular perfusion[J]. Chest, 2009, 135(6):1488-1495. |
| [59] |
Cassar A, Morgenthaler TI, Lennon RJ, et al. Treatment of obstructive sleep apnea is associated with decreased cardiac death after percutaneous coronary intervention[J]. J Am Coll Cardiol, 2007, 50(14):1310-1314.
doi: 10.1016/j.jacc.2007.06.028 pmid: 17903628 |
| [60] | Resano-Barrio MP, Arroyo-Espliguero R, Viana-Llamas MC, et al. Obstructive sleep apnoea syndrome: Continuous positive airway pressure therapy for prevention of cardiovascular risk[J]. Eur Cardiol, 2020, 15(2):e65. |
| [61] | Kaneko Y, Floras JS, Usui K, et al. Cardiovascular effects of continuous positive airway pressure in patients with heart failure and obstructive sleep apnea[J]. N Engl J Med, 2003, 348(13):1233-1241. |
| [62] | Peker Y, Glantz H, Eulenburg C, et al. Effect of positive airway pressure on cardiovascular outcomes in coronary artery disease patients with nonsleepy obstructive sleep apnea. The RICCADSA randomized controlled trial[J]. Am J Respir Crit Care Med, 2016, 194(5):613-620. |
| [63] |
Khan SU, Duran CA, Rahman H, et al. A meta-analysis of continuous positive airway pressure therapy in prevention of cardiovascular events in patients with obstructive sleep apnoea[J]. Eur Heart J, 2018, 39(24):2291-2297.
doi: 10.1093/eurheartj/ehx597 pmid: 29069399 |
| [64] |
Doherty LS, Kiely JL, Swan V, et al. Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome[J]. Chest, 2005, 127(6):2076-2084.
doi: 10.1378/chest.127.6.2076 pmid: 15947323 |
| [65] |
Park JG, Ramar K, Olson EJ. Updates on definition, consequences, and management of obstructive sleep apnea[J]. Mayo Clin Proc, 2011, 86(6):549-554.
doi: 10.4065/mcp.2010.0810 pmid: 21628617 |
| [66] |
Woodson BT, Strohl KP, Soose RJ, et al. Upper airway stimulation for obstructive sleep apnea: 5-year outcomes[J]. Otolaryngol Head Neck Surg, 2018, 159(1):194-202.
doi: 10.1177/0194599818762383 pmid: 29582703 |
| [67] |
Nakashima H, Katayama T, Takagi C, et al. Obstructive sleep apnoea inhibits the recovery of left ventricular function in patients with acute myocardial infarction[J]. Eur Heart J, 2006, 27(19):2317-2322.
doi: 10.1093/eurheartj/ehl219 pmid: 16956914 |
| [68] |
Rokkas S, Huntley C, Boon M. Hypoglossal nerve stimulation impact on a patient with obstructive sleep apnea and heart failure[J]. J Clin Sleep Med, 2021, 17 (5):1125-1127.
doi: 10.5664/jcsm.9090 pmid: 33560204 |
| [69] | Lee HM, Kim HY, Suh JD, et al. Uvulopalatopharyngoplasty reduces the incidence of cardiovascular complications caused by obstructive sleep apnea: Results from the national insurance service survey 2007-2014[J]. Sleep Med, 2018, 45(12):11-16. |
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