碘营养状态与甲状腺疾病

doi:10.3969/j.issn.1004-583X.2016.03.010

临床荟萃 ›› 2016, Vol. 31 ›› Issue (3): 272-276.doi: 10.3969/j.issn.1004-583X.2016.03.010

碘营养状态与甲状腺疾病

王绵

河北医科大学第二医院内分泌科,河北石家庄 050000

收稿日期:2015-11-03 出版日期:2016-03-05 发布日期:2016-04-18
通讯作者: 王绵, Email: wangmian66@sina.com
作者简介:王绵，河北医科大学第二医院内分泌科副主任，博士，主任医师，三级教授，硕士研究生导师。现任中华预防医学会糖尿病预防与控制委员会委员，河北省医学会内分泌学分会常委兼秘书，河北省医学会内科学分会委员，河北省医学会内科医师分会委员。《临床荟萃》杂志编委。1988年毕业至今一直从事内分泌科的临床工作，积累了丰富的临床经验。发表论文60余篇，专著5部。获河北省卫生科技进步奖3项。

Iodine nutritional status and thyroid disease

Wang Mian

Department of Endocrinology, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China

Received:2015-11-03 Online:2016-03-05 Published:2016-04-18
Contact: Wang Mian, Email: wangmian66@sina.com

摘要/Abstract

摘要： 碘是人体必须的微量元素,是甲状腺激素合成的原料,碘摄入不足在成人会引起甲状腺肿,甲状腺结节,甲状腺功能亢进等甲状腺疾病,还会引起胎儿和儿童的神经、智力发育障碍。随着食盐加碘政策的实施,碘过量与甲状腺疾病如自身免疫性甲状腺炎,甲状腺功能减退的关系也越来越受到重视。碘缺乏和碘过量均会引起甲状腺疾病,只有适量的碘摄入才会维持甲状腺的健康。

关键词: 心房颤动, 冠心病, 药物疗法, 甲状腺疾病, 碘营养, 碘缺乏, 碘过量

Abstract: Iodine is an essential micronutrient which is a component of thyroid hormones. Iodine deficiency causes thyroid disorder in adults such as goiter, nodular, hyperthyroidism, but impairs cognition and growth development in fetus and child. Universal salt iodization (USI) has been introduced in many countries, the relationship of iodine excess and thyroid diseases such as autoimmune thyroiditis and hypothyroidism is becoming more and more attention. Iodine deficiency and iodine excess can cause thyroid disease, therefore, sufficient iodine intake is important for thyroid.

Key words: atrialfibrillation, coronarydisease, drugtherapy, thyroid disease, iodine nutrition, iodine deficiency, iodine excess

中图分类号:

R581

王绵. 碘营养状态与甲状腺疾病[J]. 临床荟萃, 2016, 31(3): 272-276.

Wang Mian. Iodine nutritional status and thyroid disease[J]. Clinical Focus, 2016, 31(3): 272-276.

导出引用管理器 EndNote|Ris|BibTeX

链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2016.03.010

https://huicui.hebmu.edu.cn/CN/Y2016/V31/I3/272

参考文献

[1] WHO,ICCIDD,UNICEF.Assessment of iodine deficiency disorders and monitoring their elimination[S].Geneva:World Health Organization,2001.
[2] 中华医学会内分泌学分会、中国甲状腺疾病诊治指南编委会. 中国甲状腺疾病诊治指南.2008[J].中华内科杂志,2008,47(10):867-868.
[3] Rohner F, Zimmermann M, Jooste P, et al. Biomarkers of nutrition for development-iodine review[J]. J Nutr, 2014, 144(8):1322S-1342S.
[4] 中华医学会内分泌学分会, 中华医学会围产医学分会. 妊娠和产后甲状腺疾病诊治指南[J]. 中华内分泌代谢杂志,2012,28(5): 354-371.
[5] Ma ZF, Skeaff SA. Thyroglobulin as a biomarker of iodine deficiency: a review[J]. Throid, 2014, 24(8): 1195-1209.
[6] Zimmermann MB, Aeberli I, Andersson M, et al. Thyroglobulin is a sensitive measure of both deficient and excess iodine intakes in children and indicates no adverse effects on thyroid function in the UIC range of 100-299 mug/L: a UNICEF/ICCIDD study group report[J]. J Clin Endocrinol Metab, 2013, 98(3):1271-1280.
[7] Shi X, Han C, Li C,et al. Optimal and safe upper limits of iodine intake for early pregnancy in iodine-sufficient regions: a cross sectional study of 7190 pregnant women in China[J]. J Clin Endocrinol Metab,2015, 100(4):1630-1638.
[8] 滕卫平. 碘营养与甲状腺疾病[J]. 内科理论与实践,2010, 5(2): 112-117.
[9] Website of the International Council for the Control of Iodine Deficiency Disorders[EB/OL]. ICCIDD global network. http:// www.iccidd. org (accessed June 26, 2014)
[10] Du Y, Gao Y, Meng F, et al. Iodine deficiency and excess coexist in china and induce thyroid dysfunction and disease: a cross-sectional study[J]. PLoS One,2014, 9(11): e111937.
[11] Teng W, Shan Z, Teng X, et al. Effect of iodine intake on thyroid diseases in China[J]. N Engl J Med, 2006, 354(26): 2783-2793.
[12] Szabolcs I, Podoba J, Feldkamp J, et al. Comparative screening for thyroid disorders in old age in areas of iodine deficiency, long-term iodine prophylaxis and abundant iodine intake[J]. Clin Endocrinol (Oxf),1997, 47(1): 87-92.
[13] Tan L, Sang Z, Shen J, et al. Prevalence of thyroid dysfunction with adequate and excessive iodine intake in Hebei Province, People's Republic of China[J]. Public Health Nutr, 2015, 18(9):1692-1697.
[14] Zimmermann MB, Boelaert K. Iodine deficiency and thyroid disorders[J]. Lancet Diabetes Endocrinol,2015, 3(4):286-295.
[15] Pedersen IB, Knudsen N, Carlé A, et al. A cautious iodization program bringing iodine intake to a low recommended level is associated with an increase in the prevalence of thyroid autoantibodies in the population[J]. Clin Endocrinol (Oxf),2011,75(1):120-126.
[16] 苏俊平, 张博, 陈云霞, 等. 不同碘摄入量对自身免疫性甲状腺炎免疫机制的影响[J]. 临床荟萃, 2013, 28(8): 889-891.
[17] Hollowell JG, Staehling NW, Hannon WH, et al. Iodine nutrition in the United States. Trends and public health implications: iodine excretion data from National Health and Nutrition Examination Surveys Ⅰ and Ⅲ (1971-1974 and 1988-1994)[J]. J Clin Endocrinol Metab,1998, 83(10):3401-3408.
[18] 韩俊霞, 成兴波, 邵新宇, 等. 尿碘含量与甲状腺结节患病率的关系[J]. 江苏医药, 2015, 41(3):271-272.
[19] Zhao W, Han C, Shi X, et al. Prevalence of goiter and thyroid nodules before and after implementation of the universal salt iodization program in mainland China from 1985 to 2014: a systematic review and meta-analysis[J]. PLoS One,2014, 9(10): e109549.
[20] Pellegriti G, Frasca F, Regalbuto C, et al. Worldwide increasing incidence of thyroid cancer: update on epidemiology and risk factors[J]. J Cancer Epidemiol,2013,2013: 965212.
[21] 朱有志, 陈祥锦, 张惠灏, 等. 不同碘营养水平地区分化型甲状腺癌的流行病学研究[J]. 中国普通外科杂志, 2013, 22(11): 1450-1455.
[22] 关海霞,滕卫平,杨世明,等.不同碘摄人量地区甲状腺癌的流行病学研究[J].中华医学杂志,2001,81(8):457-458.
[23] Zimmermann MB, Galetti V. Iodine intake as a risk factor for thyroid cancer: a comprehensive review of animal and human studies[J]. Thyroid Res, 2015, 8:8.
[24] Zou S, Wu F, Guo C, et al. Iodine nutrition and the prevalence of thyroid disease after salt iodization: a cross-sectional survey in Shanghai, a coastal area in China[J]. PLoS One, 2012, 7(7): e40718.
[25] 朱素娟, 徐卫民,金行一, 等. 妊娠早期妇女碘营养与甲状腺功能异常现况研究[J]. 中华内分泌代谢杂志, 2014, 30(7):553-557.
[26] 王晓雪, 贾方, 田晶, 等.妊娠期碘营养、甲状腺自身抗体与甲状腺功能关系的研究[J]. 中华内分泌代谢杂志, 2014, 30(5): 408-410.
[27] van Mil NH, Tiemeier H, Bongers-Schokking JJ, et al. Low urinary iodine excretion during early pregnancy is association with alteration in executive functioningin children[J]. J Nutr, 2012, 142( 12 ): 2167-2174.
[28] Guan H, Li C, Li Y. High iodine intake is a risk factor of post-partum thyroiditis: result of a survey from Shenyang, China[J]. J Endocrinol Invest, 2005, 28(10): 876-881.

碘营养状态与甲状腺疾病

Iodine nutritional status and thyroid disease

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 15

编辑推荐

Metrics

本文评价

[1]	王奕涵, 秦旭雁, 韩宣泽, 王樱洁, 高菲菲, 陈春红, 张岭楠, 张芳. 利伐沙班用于HASBLED评分≥3分的高龄非瓣膜性心房颤动患者的有效性和安全性[J]. 临床荟萃, 2024, 39(2): 121-124.
[2]	李雯琳, 张志. 心房颤动患者左心耳形态结构和功能与左心耳血栓及心源性卒中的关系研究进展[J]. 临床荟萃, 2024, 39(2): 168-171.
[3]	魏宇涵, 赵亚楠, 张桂彬, 吴雨晴, 董博华, 扈家源, 杨文琦. 单核细胞/高密度脂蛋白胆固醇比值、红细胞分布宽度、尿酸与冠心病患者冠状动脉病变严重程度的相关性[J]. 临床荟萃, 2023, 38(9): 796-801.
[4]	张娜文, 黄少敏, 田利民. 2型糖尿病与帕金森病相关性研究的进展[J]. 临床荟萃, 2023, 38(9): 845-850.
[5]	王震, 杨晓月, 李少杰, 王贤, 陈淑霞, 谷剑. 射血分数保留的心力衰竭合并心房颤动患者临床特征及再入院危险因素[J]. 临床荟萃, 2023, 38(4): 308-314.
[6]	宗廷妮, 戴光荣, 赵晓宇, 李瑞风, 柴聪敏. 代谢相关脂肪性肝病靶向药物治疗进展[J]. 临床荟萃, 2023, 38(4): 373-376.
[7]	王子佳, 王九雪, 王天俊. 抗甲状腺抗体阳性的视神经脊髓炎1例并文献复习[J]. 临床荟萃, 2023, 38(3): 264-267.
[8]	张芳, 张伊超, 贾辛未, 李建龙, 陈春红. 心房颤动高CHA2DS2-VASc评分≥75岁住院患者随访1年结果分析[J]. 临床荟萃, 2023, 38(2): 117-120.
[9]	刘亚鑫, 郭岚, 王泽凯, 牛凯. 慢性肾脏病合并骨质疏松症治疗的研究进展[J]. 临床荟萃, 2023, 38(12): 1146-1149.
[10]	师佩华, 林彦琳, 毕丽妨. NLR、PLR及MLR与2型糖尿病合并冠心病患者的相关性研究[J]. 临床荟萃, 2023, 38(11): 996-1001.
[11]	张上仕, 朱红艳, 李楠, 陈鹰熙. 冠心病合并2型糖尿病患者冠状动脉病变与胰岛素抵抗的相关性分析[J]. 临床荟萃, 2023, 38(1): 46-49.
[12]	伊鑫, 刘灿章, 刘强, 王聪, 高腾, 闫杰. 冠心病患者合并焦虑抑郁对冠状动脉斑块成分及性质的影响[J]. 临床荟萃, 2023, 38(1): 50-54.
[13]	王宁, 李勇. 簇集蛋白在心血管疾病中的研究进展[J]. 临床荟萃, 2022, 37(9): 842-845.
[14]	马静红, 杨倩, 贾永建, 党懿. 心房颤动导管消融围术期不间断新型口服抗凝剂和不间断华法林抗凝导致心脏压塞风险的荟萃分析[J]. 临床荟萃, 2022, 37(9): 773-778.
[15]	张海福, 叶向晴, 陈者旭, 陈施鉴, 杨栋, 张邢炜. 适量运动对心房颤动患者预后的影响:系统综述与Meta分析[J]. 临床荟萃, 2022, 37(6): 485-489.