临床荟萃

• 论著 • 上一篇    下一篇

日照市部分支气管哮喘患者用药情况调查

  

  1. 日照市结核病防治所  呼吸内科,山东 日照  276800
  • 出版日期:2017-05-05 发布日期:2017-05-05
  • 通讯作者: 通信作者:冯连彩,Email:wgflc@163.com

Medication in patients with bronchial asthma in Rizhao city

  1. Department of Respiratory  Medicine,Tuberculosis Institute of Rizhao, Rizhao 276800, China
  • Online:2017-05-05 Published:2017-05-05
  • Contact: Corresponding author: Feng Liancai, Email: wgflc@163.com

摘要:
目的调查日照市部分支气管哮喘患者的用药情况,了解我市支气管哮喘患者治疗的现状。方法通过调查问卷的形式调查所有来我所就诊的既往已经确诊的初诊支气管哮喘患者229例,包括一般资料、具体用药的种类、剂型、时间等。结果229例哮喘患者中,使用茶碱类药物和短效β2受体激动剂药物(包括口服和吸入两种剂型)的患者比例分别是78.6%、68.1%,吸入性糖皮质激素的比例在44.5%,使用非正规来源药物的比例在36.2%;使用口服糖皮质激素患者的平均使用时间明显长于使用吸入性糖皮质激素患者(P<0.01);使用非正规来源药物的患者和使用正规来源药物的患者年龄和病程比较差异有统计学意义(P<0.05)。结论我市支气管哮喘患者的用药不规范,以长期使用速效缓解类的药物如茶碱类和短效β2受体激动剂药物为主,吸入性糖皮质激素的比例偏低,口服糖皮质激素仍占有一定的比例,非正规来源的药物多见于病程长的老年人使用。

关键词: 哮喘, 茶碱, 肾上腺素能&beta, 2受体激动剂, 糖皮质激素类

Abstract: ObjectiveTo investigate the medication in patients with bronchial asthma, so as to understand the current status of treatment in bronchial asthma patients in Rizhao city. MethodsA total of 229 patients were selected in a face to face questionnaire survey. The disease identification, history and medication  including the kinds, dosage form and time of medication  were surveyed. ResultsThe percentages of 229 patients with theophylline and shortacting beta2 receptor agonists (included oral and inhale types) were 78.6% and  68.1%, respectively; The percentage with inhaled corticosteroids(ICS)  was  44.5%; The percentage with nonconformal drugs was 36.2%; The average time in patients with oral hormone was longer than that of  ICS(P<0.01); There was statistical significance in age and disease  course  between nonconformal and conformal drugs  (P<0.05).ConclusionIn Rizhao city, the medication in patients with bronchial asthma was not reasonable; the drugs of theophylline and shortacting beta2 receptor agonists in bronchial asthma were prior to the drugs of ICS. There was still  a certain proportion of  patients with oral hormone, but patients with nonconformal drugs were older and their disease courses were longer than those with conformal drugs.

Key words: asthma, theophylline, adrenergic beta2 receptor agonists;glucocorticoids