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拘禁球囊技术在冠状动脉分叉病变介入治疗中有效性的Meta分析

  

  1. 南华大学附属永州市中心医院北院 心内科, 湖南 永州 425000
  • 出版日期:2018-11-05 发布日期:2018-12-10
  • 通讯作者: 通信作者:曹斌,Email:caobinyzs@163.com

Jailed balloon technique for coronary bifurcation lesions: a metaanalysis

  1. Department of Cardiology, North Hospital, the Centre Hospital of Yongzhou Affiliated to University of South China,  Yongzhou 425000, China
  • Online:2018-11-05 Published:2018-12-10
  • Contact: Corresponding author: Cao Bin, Email: caobinyzs@163.com

摘要: 目的  探讨拘禁球囊技术(JBT)在冠状动脉分叉病变介入治疗中的有效性。方法 通过PubMed、EMbase、Cochrane Library、中国知网、万方等数据库收集使用JBT治疗冠状动脉分叉病变的相关研究文献。应用meta分析对所收集的文献进行综合定量评价,以使用JBT作为JBT组,并取传统边支保护技术(拘禁导丝或边支球囊对吻)的作为对照组,运用REVMAN5.3进行统计学处理。结果 共纳入文献9篇,累计病例JBT组380例,对照组366例。Meta分析结果显示:与对照组比较,JBT组缩短了经皮冠状动脉介入术(percutaneous coronary intervention,PCI)手术时间(WMD=-20.41, 95%CI=-24.00~-16.82, P<0.05); JBT组减少了边支闭塞、夹层或慢血流等并发症的发生率(RR=0.40, 95%CI=0.24~0.66,P<0.05),未能降低再发心肌梗死、靶血管重建,严重心力衰竭等心血管不良事件发生率(RR=0.58, 95%CI=0.31~1.07,P=0.08)。结论  与传统边支保护技术比较,JBT可缩短手术时间,减少术中边支闭塞、夹层或慢血流等并发症的发生率,未减少主要心血管不良事件发生率。

关键词: 冠状动脉疾病, 冠状动脉分叉病变, 拘禁球囊, meta分析

Abstract: ObjectiveTo explore the jailed balloon(JBT) technique for coronary bifurcation lesions. MethodsThe database PubMed, EMBASE, the Cochrane Library database, CNKI and WanFang database were used to collect the relevant research literature on the application  of JBT to the treatment of coronary bifurcation lesions. The  metaanalysis was applied to the comprehensive quantitative evaluation of the literature collected. The patients treated with JBT was set as a group, while those who hadn't belong to the control group.REVMAN 5.3 was used for statistical analysis. ResultsA total of 8 studies were included, which involved 360 cases as JBT group and 585 as the control group. Compared with the control group,  JBT group saw their time of percutaneous coronary intervention(WMD=-20.41, 95%CI=-24.00-16.82,P<0.05) significantly shortened,  and lower incidence of complications such as side support occlusion, dissection or slow blood flow (RR=0.40,95%CI=0.240.66,P<0.05), and there were no significant differences in main adverse coronary event (MACE)(RR=0.58,95%CI=0.311.07,P=0.08).ConclusionCompared with the traditional sidebranch (SB) protection technique, JBT can shorten the operation time, reduce the incidence of complications of SB occlusion, dissection or slow blood flow,  and the incidence of MACE events.

Key words: coronary artery disease;coronary bifurcation lesions, jailed balloon, meta analysis