阻塞性睡眠呼吸暂停低通气综合征与支气管哮喘关系的研究进展

doi:10.3969/j.issn.1004-583X.2023.10.015

摘要/Abstract

摘要：

阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome, OSAHS)是一种在睡眠期间反复发作的呼吸暂停或低通气疾病,主要指每晚睡眠中反复发作的呼吸暂停在30次以上或睡眠呼吸暂停/低通气指数(apnea-hypopnea index, AHI)≥5次/h,主要表现为夜间睡眠时打鼾并伴有呼吸暂停及嗜睡、注意力不集中、记忆力下降等日间症状。支气管哮喘(bronchial asthma, BA)是一种有多种表型的慢性炎症性疾病,特征是慢性炎症、可逆性气流阻塞和支气管高反应性。这2种呼吸系统常见疾病有相似病理生理和临床表现。近年,同时患有2种疾病的患者数量不断增加,可能引发心、脑、肺、血管疾病并发症,导致多器官功能损害,严重威胁生命和健康。本综述对OSAHS合并BA的重叠综合征(overlap syndrome,OS)流行病学、病理作用机制及治疗进行综述,以期进一步推进该病的研究方向。

关键词: 睡眠呼吸暂停, 阻塞性, 哮喘, 哮喘-慢性阻塞性肺疾病重叠综合征, 胃食管反流, 持续气道正压通气

中图分类号:

R563

郑志璇, 平芬, 李萍, 吴国飘. 阻塞性睡眠呼吸暂停低通气综合征与支气管哮喘关系的研究进展[J]. 临床荟萃, 2023, 38(10): 940-943.

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链接本文: https://huicui.hebmu.edu.cn/CN/10.3969/j.issn.1004-583X.2023.10.015

https://huicui.hebmu.edu.cn/CN/Y2023/V38/I10/940

图/表 1

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