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Meta analysis of the effectiveness of bronchofiberscope lavage in treatment of acute lung abscess

  

  1. a.Postgraduate Training Base; b.Department of Respiratory Medicine,  No.967 Hospital of
    PLA Joint Logistics Support Force,  Jinzhou Medical University, Dalian 116021,  China
  • Online:2019-10-20 Published:2019-12-09
  • Contact: Corresponding author: Liu Zhongyang, Email: Email:2030622263@qq.com

Abstract: Objective  To prove the effectiveness of bronchofiberscope lavage in the treatment of acute lung abscess and provide basis for its priority in clinical work. Methods  Chinese and English databases such as (CNKI),  (VIP),  Wanfang,  PubMed,  Embase,  Cochrane,  etc. were searched for the clinical effectiveness of bronchofiberscope lavage in the treatment of acute lung abscess from January 1,  2010 to December 1,  2018. Two researchers obtained relevant data according to the original document inclusion and exclusion criteria,  and the quality of the included literature was evaluated by the Cochrane bias risk assessment tool. Statistical analysis was performed with Mevman 5.3 software.Results  Altogether, 20 articles were included in the literature,  and a total of 1332 patients were analyzed. The results showed that bronchofiberscope lavage for acute lung abscess was more effective than conventional treatment group (RR=1.27,  95%CI[1.18,  1.37],  P<0.01),  FEV1 level (WMD=0.36,  95%CI [ The improvement of 0.29, 0.42],  P<0.01)  and its PaO2 level (WMD=9.12,  95%CI[7.94, 10.30],  P<0.01)   was significantly higher than that of the conventional treatment group,  and its hospitalization time (WMD=-9.96,  95%CI[-12.95,-6.96],  P<0.01),  body temperature recovery time (WMD=-4.29,  95%CI[-5.29, -3.29],  P<0.01),  cough and sputum relief time (WMD=-3.91,  95%CI[-4.43,-3.40], P<0.01),  diminution time of abscess (SMD=-1.74,  95%CI[-2.63,-0.86], P=0.01)  were also shorter than thoseofthe conventional treatment group. Conclusion  Current clinical research data show thatfiberoptic bronchoscopy has its unique advantages in the treatment of acute lung abscess.

Key words: acute lung abscess, bronchofiberscope, bronchoalveolar lavage, effectiveness, metaanalysis