Abstract: Objective  To systematically explore the risk factors for postoperative cardiovascular events in patients with acute STsegment elevation myocardial infarction (STEMI) undergoing coronary intervention.  Methods  The data of relevant casecontrol trials from 2010 to 2020 were collected. The Study quality evaluation with NewcastleOttawa Scale (NOS) scale. Metaanalysis on literatures was conducted by using RevMan 5.2 software. Results  Factors influencing adverse events after PCI in STEMI patients were advanced age, diabetes mellitus，Killip class ≥Ⅱ，EF values，maintenance of high systolic blood pressure, emergency PCI startup time, Gensini score，left main stem disease，multivessel disease≥2，hsCRP, NTproBNP，CKMB，intravenous tirofiban, TIMI flow grade（P<0.01）.Conclusion  Older age，history of diabetes mellitus, Killip class ≥Ⅱ，high Gensini score，multivessel disease≥2, increased hsCRP levels, increased NTproBNP levels, increased CKMB levels and TIMI flow grade≤2 are independent risk factors for patients after primary PCI , While high preoperative EF values, high preoperative systolic pressure and intravenous tirofiban are protective factors.

Key words: myocardial infarction, percutaneous coronary intervention, cardiovascular adverse events, metaAnalysis