Abstract:

Objective To explore the effects of pharmaceutical services and interventions in discharged patients with acute myocardial infarction(AMI). Methods A total of 140 discharged patients with AMI treated in Cardiovascular Medicine Department of the Hospital were selected and randomly divided into two groups (70 cases in each group), routine medical advices were implemented for patients in the control group, professional pharmaceutical interventions were implemented for patients in the observation group on the basis of such advices implemented for patients in the control group. The patients in both groups were followed up for 12 months, score of Morisky Medication Adherence Scale 8-item version(MMAS-8), incidence rate of missed dosing and prognosis of patients in two groups were compared. Results The difference in the effect of pharmaceutical intervention on medication adherence was statistically significant (P<0.01);The difference in the effect of the time on medication adherence was statistically significant (P<0.01);The interaction was statistically significant between groups and time (P<0.01), the missed dosing of patients in the observation group in the 3 months, 6 months and 12 months after interventions were lower than those of patients in the control group(all P<0.01). AMI recurrence rate (7.14%) and rehospitalization rate (8.57%) of patients in the observation group after 12-month follow-up period were lower those of patients in the control group (18.57%, 21.43)(P<0.05). Conclusion The pharmaceutical interventions implemented on discharged patients with AMI can improve the medication adherence of patients, reduce the rate of disease recurrence, and improve the prognosis of patients.

Key words: pharmaceutical service, myocardial infarction, prognosis, medication adherence