Abstract: Objective  To observe the clinical features of patients with diabetic cranial neuropathy (DCN),  and analyze the risk factors for DCN and the influence factors for prognosis. Methods  The clinical features of  36 patients with DCN (DCN group) and 40 diabetic patients (DM group)  were analyzed and compared. Multifactor logistic regression was used to analyze the risk factors of diabetic patients with DCN and the risk factors affecting the prognosis of DCN. Results  ①The DM course,  FPG,  2 hPG,  HbA1c and the ratio of smoking and DR were significantly higher in DCN group than those in DM group (P＜0.01). ②The levels of Vs,  Vm,  PI and RI were significantly higher in DCN group than those in DM group (P＜0.01). ③Logistic regression analysis showed that FPG,  2 hPG,  HbA1c and with DR were risk factors for diabetic patients with DCN; DM course,  HbA1c and with hypertension were influence factors for prognosis of  DCN patients. Conclusion  Positive control of blood sugar is the key to prevent the diabetic patients with DCN; the prognosis of DCN patients may be related to  long DM course,  higher HbA1c and hypertension.

Key words: diabetic neuropathies, risk factors, prognosis