Abstract:

Objective To evaluate the clinical characteristics and relevant factors of ankylosing spondylitis(AS) with hip involvement. Methods A total of 331 AS patients hospitalized in the Third Hospital of Hebei Medical University were divided into normal AS group and AS with hip involvement group according to if they were concurrent with hip involvement. The normal information, laboratory indicators and past medication history were compared for the risk factors between the two groups. Results Totally 244 (73.7%) cases were hip involvement among 331 AS patients. Compared with normal AS group, AS with hip involvement group had decreased age at onset (P<0.01), increased levels of C-reactive protein(CRP) and platelet(PLT)(P<0.05), increased male ratio, increased past hormone use rate, increased proportion of osteoporosis(P<0.05), and decreased incidence of ophthalmitis (P<0.05). The result showed that the risk factors of AS with hip involvement were male (OR=4.29, P=0.007) and pathogenesis in low age (OR=2.98, P=0.003). Conclusion Hip involvement is more common in AS patients, and with serious illness the patients are more prone to osteoporosis. Male and early-onset are the risk factors of AS with hip involvement.

Key words: spondylitis, ankylosing, osteoarthritis, hip, osteoporosis, endophthalmitis