Efficacy of  anti  tumor necrosis factor α  preparation  in achilles tendon enthesitis

doi:10.3969/j.issn.1004-583X.2018.05.017

Abstract

Abstract: Objective To explore the value of anti tumor necrosis factor α (TNFα) preparation in achilles tendon enthesitis in ankylosing spodylitis(AS) by ultrasonics. Methods We chose 32 AS patients who received anti TNFα preparation as experiment group and 29 AS patients who got conventional therapy as control group. The ultrasound images, erythrocyte sedimentation rate(ESR) and C reactive protein(CRP) were compared after six weeks of treatment between two groups. Results Compared with the control group, the ultrasound scores and clinic scores of achilles tendon enthesitis in experiment group witnessed significant reduction（both P<0.01). The changes of ESR and CRP in experiment group were more significant than those in control group(both P<0.01). Conclusion Anti TNFα preparation can improve the achilles tendon enthesitis in AS patients, which has been proved by ultrasonics.

Key words: spondylitis ankylosing, achilles tendon, ultrasonography, tumor neerosis factoralpha

Xie Jianli, Chen Haiying, Wang Junxiang, Zhang Ying, Xu Jinrong. Efficacy of anti tumor necrosis factor α preparation in achilles tendon enthesitis[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2018.05.017.

Add to citation manager EndNote|Ris|BibTeX

URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2018.05.017

https://huicui.hebmu.edu.cn/EN/Y2018/V33/I5/431

[1]	Li Zhiyong. Transient peripheral carotid inflammation syndrome diagnosed by ultrasonography: A case report and literature review [J]. Clinical Focus, 2023, 38(11): 1027-1030.
[2]	Xu Jingran, Li Feifei, Xie Chengxin, Gong Hui, Luan Qiyun, Li Li. Application of endobronchial ultrasound transbronchial lung biopsy with guide sheath and rapid on-site evaluation in the diagnosis of bacteriologically-negative pulmonary tuberculosis [J]. Clinical Focus, 2022, 37(3): 220-224.
[3]	Liu Ruixi, Yi Qijian. Value of platelet volume and platelet distribution width in children Kawasaki disease [J]. Clinical Focus, 2021, 36(9): 824-827.
[4]	Yin Xiaokang, Zhang Jiping, Zhu Yugang, Shen Hongxia, Wang Defeng. Effect of empagliflozin on ventricular remodeling in patients with type 2 diabetes mellitus and coronary heart disease [J]. Clinical Focus, 2021, 36(8): 713-718.
[5]	Ma Guilan, Min Ju. Evaluation value of severity and prognosis of Lung ultrasound combined with serum NT-proBNP and sFlt-1 on acute respiratory distress syndrome in patient [J]. Clinical Focus, 2021, 36(12): 1110-1113.
[6]	Wang Chao, Wan Duo, Li Sali, Wang Xi. Evaluation of carotid Doppler ultrasonography in degree and hemodynamics of atherosclerosis of chronic kidney disease [J]. Clinical Focus, 2021, 36(11): 1009-1012.
[7]	Lyu Yixuan, Lu Zhanfei, Sun Nianzhe, Li Fuhan, Liu Rong. Systematic review on the efficacy of dual-energy CT and ultrasound in the diagnosis of gout [J]. Clinical Focus, 2021, 36(1): 5-7.
[8]	Zhang Hang, Ma Jie, Ma Qianli, An Jinghui, Li Luyu, Zhang Jieqiong, Shi Fengwu. Prevention of recurrence of cryptic stroke by interventional closure of patent foramen ovale [J]. Clinical Focus, 2020, 35(1): 28-31.
[9]	Zhang Jingchao, Ma Yangyang, Li Shuangbiao, Lan Yongzhen, Wang Xiao. Value of endoscopic ultrasonography in the diagnosis of lowgrade appendix mucinous neoplasm [J]. Clinical Focus, 2019, 34(9): 799-801.
[10]	Liu Enshuo, Yang Fei, Sun Siyu. Principle and clinical application of endoscopic ultrasoundelastography [J]. Clinical Focus, 2019, 34(9): 777-780.
[11]	Li Shiyu, Wang Kaixuan, Jin Zhendong. Application and research progress of endoscopic ultrasonography in the diagnosis of pancreatic cancer [J]. Clinical Focus, 2019, 34(9): 773-776.
[12]	Zhao Xuegang1, Liu Xiaomin1, Li Li1, Zhou Wei2. Predictive value of musculoskeletal ultrasonography in clinical remission of disease recurrence in patients with rheumatoid arthritis [J]. Clinical Focus, 2019, 34(9): 802-804.
[13]	Wei Xiaohong1, Shang Hong1, Zhou Lizhu1, Yang Xiaoyan1, Zhang Jianwei1, Zhang Xuefan2. Applied value of the score of pulsed wave Doppler ultrasonography joint Apgar in diagnosis of hypoxicischemic encephalopathy [J]. Clinical Focus, 2019, 34(7): 646-650.
[14]	Hu Chenghuan, Zhang Lina, Chinese Critical Ultrasound Study Group. Renal perfusion pressure: what is appropriate？ [J]. Clinical Focus, 2019, 34(7): 590-594.
[15]	Wang Xiaoting, Wang Guangjian, Zhang Hongmin, Chinese Critical Ultrasound Study Group. Critical renal ultrasound: evaluation of renal hemodynamics [J]. Clinical Focus, 2019, 34(7): 581-583.

Efficacy of anti tumor necrosis factor α preparation in achilles tendon enthesitis

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments