Prevention of recurrence of cryptic stroke by interventional closure of patent foramen ovale

doi:10.3969/j.issn.1004-583X.2020.01.004

Abstract

Abstract: Objective To explore the safety and effectiveness of patent foramen ovale(PFO) closure, and further discuss clinical significance of interventional closure of PFO.Methods Totally 90 patients receiving PFO interventional closure in our hospital from January to July in 2019 were selected.All patients received transthoracic echocardiography (cTTE) and transesophageal echocardiography (TEE) to confirm the presence of right to left shunt with PFO.The successful occlusion was immediately performed by bedside transthoracic echocardiography (TTE), and the blocking device and shunt were observed.Three months after the operation, transthoracic echocardiography (cTTE) and brain CT were performed.Results All patients were successfully placed with the occlusive device, and transthoracic echocardiography immediately confirmed that the occlusive device was in normal position, the mitral valve and tricuspid valve function were good, no residual shunt was observed, and no intraoperative or postoperative complications occurred.After the follow-up of threemonths, headache symptoms completely disappeared in 58.9% of the patients, significantly improved in 34.4% of the patients, and the frequency of attack was significantly lower than before.The total effectiveness was 93.3%. Among the 27 patients with unilateral limb numbness and fatigue before the operation, 19 patients showed complete disappearance of limb numbness and fatigue symptoms after the operation, and eight patients showed different degrees of remission of limb numbness and fatigue symptoms although they did not completely disappear.Before the operation, eightcases with nausea and vomiting, postoperative symptoms completely disappeared.The positive rate of right echocardiography by transthoracic echocardiography at three months after surgery was 5.6%(5/90).The reexamination of brain CT three months after surgery indicated that no new infarction was found in all 90 patients in this study, and the incidence of recurrent stroke was 0%.Conclusion Interventional closure therapy for PFO can definitely relieve the clinical symptoms and pain of patients, reduce residual shuntand the risk of recurrent stroke. It is a safe and effective treatment method, which has a guiding significance for the treatment of PFO.

Key words: heart defects, , congenital, foramen ovale, , patent, ultrasonography, , interventional

Zhang Hang, Ma Jie, Ma Qianli, An Jinghui, Li Luyu, Zhang Jieqiong, Shi Fengwu. Prevention of recurrence of cryptic stroke by interventional closure of patent foramen ovale[J]. Clinical Focus, doi: 10.3969/j.issn.1004-583X.2020.01.004.

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URL: https://huicui.hebmu.edu.cn/EN/10.3969/j.issn.1004-583X.2020.01.004

https://huicui.hebmu.edu.cn/EN/Y2020/V35/I1/28

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Prevention of recurrence of cryptic stroke by interventional closure of patent foramen ovale

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