关键词: 关节炎, 类风湿, 胸腔积液

Abstract: Objective To investigate the feature of pleural effusion in patients with rheumatoid arthritis for the recognition of the disease.Methods The clinical feature of pleural effusion in patients with rheumatoid arthritis was retrospectively analyzed.Results There was no pleural effusion in patients with remission of rheumatoid arthritis, all patients with pleural effusion were in active phase of the disease, especially in moderate and high active phase, significant difference in the number of patients was detected in low, moderate and high active phases of rheumatoid arthritis between groups (P＜0.05). The average levels of erythrocyte sedimentation rate and C-reactive protein were significantly higher in pleural effusion group than in non-pleural effusion group. The positive rates of rheumatoid factor and anti-cyclic citrullinated peptide antibody were significantly higher in pleural effusion group than in non-pleural effusion group (P＜0.05). The average number of joint tenderness and swollen joint was significantly higher in pleural effusion group than in non-pleural effusion group and the average time of morning stiffness was significantly longer in pleural effusion group than in non-pleural effusion group (P＜0.05). Compared with non-pleural effusion group, the remission number of patients was significantly decreased in pleural effusion group (P＜0.05), and the number of new joint deformity was significantly increased in pleural effusion group (P＜0.05).Conclusion Rheumatoid arthritis patients present pleural effusion as an active signal of disease, which was positively correlated with immune index and clinical symptom and should get rigorously treated.

Key words: arthritis, rheumatoid, pleural effusion