临床荟萃

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糖皮质激素在溃疡性结肠炎治疗中的合理应用

  

  1. 河北医科大学第四医院 消化内科,河北 石家庄 050011
  • 出版日期:2016-08-05 发布日期:2016-07-30
  • 通讯作者: 通信作者:李胜棉,Email:shengmianli2013@163.com
  • 作者简介:李胜棉,主任医师,教授,河北医科大学第四医院消化内科副主任,河北省优秀省管专家。河北省医师协会肝病学分会副主任委员,河北省中西医结合学会肝病学分会副主任委员,河北省抗癌协会肿瘤转移专业委员会副主任委员,河北省医学会肿瘤学分会肝癌专业委员会副主任委员,河北省医学会消化学分会常委。

Rational application of corticosteroids in ulcerative colitis

  1. Department of Gastroenterology and Hepatology, the Fourth Hospital of
    Hebei Medical University,Shijiazhuang 050011,China
  • Online:2016-08-05 Published:2016-07-30
  • Contact: Corresponding author:Li Shengmian,Email:shengmianli2013@163.com

摘要: 糖皮质激素能有效诱导活动性溃疡性结肠炎缓解,同时伴有诸多的不良反应。由于大规模随机对照临床研究的缺乏,糖皮质激素在溃疡性结肠炎治疗中的应用标准模式尚不清晰。降低糖皮质激素使用风险,最大化其疗效需要选择适合人群,在适当时机给予恰当药物。本文结合近年发表的专家共识意见,探讨溃疡性结肠炎治疗中糖皮质激素的合理应用。

关键词: 糖皮质激素类, 结肠炎, 溃疡性

Abstract: Corticosteroids are efficacious to induce remission in patients with active ulcerative colitis, whilst accompanying by adverse events. Due to the lack of largescale randomized controlled clinical study, standard mode for application of corticosteroids in the treatment of ulcerative colitis is not very clear. To reduce corticosteroids use risk and maximize efficacy need  for right patients, appropriate agents should be used at the right time. According to the expert consensus published in recent years, a systematic review has been performed to examine this issue.

Key words: corticosteroids, colitis, ulcerative