摘要:
原发性干燥综合征(primary Sjögren's syndrome, pSS)是一种以淋巴细胞增殖及侵犯外分泌腺为特征,不伴有任何潜在疾病的慢性炎症性自身免疫病, 可造成多系统损害。儿童发病率低,但肾损害突出,主要为肾小管间质性肾炎、肾小管酸中毒,而肾小球肾炎少见。pSS患儿肾损害起病隐匿,临床表现多样,是患儿远期预后的主要影响因素之一,早期发现可提高患儿生活质量。本文就儿童pSS肾损害的流行病学、临床表现、实验室检查及治疗等做一综述,以提高临床医师对儿童pSS合并肾损害的认识。
中图分类号:
曹阳, 李崇巍. 儿童原发性干燥综合征合并肾损害的研究进展[J]. 临床荟萃, 2022, 37(2): 188-192.
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